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Treatment of Subacromial Impingement Syndrome: Platelet-Rich Plasma or Exercise Therapy? A Randomized Controlled Trial

机译:肩峰下冲击综合征的治疗:富含血小板的血浆还是运动疗法?随机对照试验

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Background: Subacromial impingement syndrome (SAIS) is the most common disorder of the shoulder. The evidence for the effectiveness of treatment options is inconclusive and limited. Therefore, there is a need for more evidence in this regard, particularly for long-term outcomes. Hypothesis: Platelet-rich plasma (PRP) would be an effective method in treating subacromial impingement. Study Design: Randomized controlled trial; Level of evidence, 1. Methods: This was a single-blinded randomized clinical trial with 1-, 3-, and 6-month follow-up. Sixty-two patients were randomly placed into 2 groups, receiving either PRP or exercise therapy. The outcome parameters were pain, shoulder range of motion (ROM), muscle force, functionality, and magnetic resonance imaging findings. Results: Both treatment options significantly reduced pain and increased shoulder ROM compared with baseline measurements. Both treatments also significantly improved functionality. However, the treatment choices were not significantly effective in improving muscle force. Trend analysis revealed that in the first and third months, exercise therapy was superior to PRP in pain, shoulder flexion and abduction, and functionality. However, in the sixth month, only shoulder abduction and total Western Ontario Rotator Cuff score were significantly different between the 2 groups. Conclusion: Both PRP injection and exercise therapy were effective in reducing pain and disability in patients with SAIS, with exercise therapy proving more effective.
机译:背景:肩峰以下撞击综合征(SAIS)是最常见的肩部疾病。有关治疗选择有效性的证据尚无定论,而且是有限的。因此,在这方面需要更多的证据,特别是对于长期结果。假设:富含血小板的血浆(PRP)将是治疗肩峰以下撞击的有效方法。研究设计:随机对照试验;证据级别:1。方法:这是一个单盲随机临床试验,随访1个月,3个月和6个月。 62例患者随机分为两组,分别接受PRP或运动疗法。结果参数是疼痛,肩部活动范围(ROM),肌肉力量,功能和磁共振成像结果。结果:与基线测量值相比,两种治疗方法均显着减轻了疼痛并增加了肩部ROM。两种处理方法也都大大改善了功能。但是,治疗选择对改善肌肉力量没有显着效果。趋势分析显示,在头三个月中,运动疗法在疼痛,肩膀屈伸,外展和功能方面优于PRP。然而,在第六个月,两组之间仅肩关节外展和西安大略肩袖总分明显不同。结论:PRP注射和运动疗法均可有效减轻SAIS患者的疼痛和残疾,运动疗法更有效。

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