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The Role of Tibial Osteotomy in the Outcome of Meniscus Allograft Transplantation

机译:胫骨截骨术在半月板异体移植结果中的作用

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Objectives: Meniscal allograft transplantation (MAT) is indicated to relieve pain and improve function and hopefully to delay the onset of osteoarthritis in patients with meniscus deficiency. The purpose of this study was to compare the effect of perioperative cartilage status on survivorship and whether this is influenced by a concurrent tibial osteotomy. Methods: We reviewed a consecutive series of 45 MATs in 42 patients with a minimum post-surgical time of four years. Patients were divided into two groups using the Outerbridge Cartilage Score (OSC) to group 1 (minimal cartilage damage of grade 0-2) and group 2 (severe cartilage damage of grade 3-4). Pre- and post-operative outcome scores were collected using the Lysholm, Tegner, Oxford Knee Score (OKS) and International Knee Documentation Committee (IKDC) subjective knee form. Survival end points were transplant removal and knee arthroplasty. Results: The mean post-surgical follow-up for patients in group 1 (n=14, age 32.0 +/- 9.8) and group 2 (n=31, age 36.2 +/- 10) was 10.6 years (SD +/-3.35) and 7.1 (SD+/-3.34) respectively. There was no significant difference in the mean age between the two groups (p-value 0.221, CI -2.62 to 11). Patients in group 1 demonstrated no failures of the MAT over the time frame evaluated. Group 2 (n=31) had a 74.2% survival of MATs. The clinical outcomes improved in all groups with no significant difference between group 1 and group 2. Those patients in the osteotomy group did not have a statistically significant different survival (Mantel-cox test p-value of 0.922) or clinical outcome. Conclusion: Patient with minimal cartilage status have improved MAT survivorship but both groups benefit clinically. Tibial osteotomy, when indicated, does not influence the outcome of MAT.
机译:目的:半月板同种异体移植(MAT)可减轻疼痛并改善功能,并有望延迟半月板缺乏症患者的骨关节炎发作。这项研究的目的是比较围手术期软骨状态对生存率的影响,以及这是否受到并发胫骨截骨术的影响。方法:我们回顾了42例患者的连续45项MAT,一系列术后最短时间为四年。使用外桥软骨评分(OSC)将患者分为两组,第1组(0-2级的最小软骨损伤)和第2组(3-4级的严重软骨损伤)。使用Lysholm,Tegner,Oxford膝关节评分(OKS)和国际膝关节文献委员会(IKDC)主观膝关节形式收集术前和术后结果评分。生存的终点是移植去除和膝关节置换术。结果:第一组(n = 14,32.0 +/- 9.8岁)和第二组(n = 31,36.2 +/- 10)的患者术后平均随访时间为10.6年(SD +/- 3.35)和7.1(SD +/- 3.34)。两组之间的平均年龄没有显着差异(p值0.221,CI -2.62至11)。第一组的患者在评估的时间内未表现出MAT失败。第2组(n = 31)的MAT生存率为74.2%。所有组的临床结局均有改善,第1组和第2组之间无显着差异。截骨组的那些患者的生存率(Mantel-cox检验p值为0.922)没有统计学差异。结论:软骨状态最低的患者可提高MAT生存率,但两组均在临床上受益。指示胫骨截骨术不会影响MAT的结果。

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