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Thromboembolic Events after Arthroscopic Knee Surgery: Increased Risk at High Altitude

机译:关节镜膝关节手术后的血栓栓塞事件:高海拔地区的风险增加

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Objectives: The purpose of this study was evaluate the incidence of thromboembolic events in patients undergoing arthroscopic surgery of the knee in surgery centers located at elevations near sea level and comparing those rates with the patients undergoing the same operations at surgery centers located in cities at high altitude. Methods: A retrospective review was conducted using a database of a major health care system with surgery centers located throughout the United States. Over 115 surgery centers located in 15 different states were analyzed for any reported thromboembolic events including deep vein thromboses (DVT) and pulmonary embolism (PE) in patients who had undergone knee arthroscopy over a 2 year period. The surgical centers located at elevations lower than 1000 ft were considered sea level centers. Those centers located at elevations above 4000 ft were considered high altitude centers. Any surgical center located between 1000 ft and 4000 ft elevation was excluded. Results: 35,877 patients underwent a knee arthroscopy procedure at a low altitude center between 2011-2012. 10,181 patients underwent a knee arthroscopy procedure at a high altitude center between 2011-2012. During that same time period, 45 total VTEs including 12 PEs occurred at centers considered low altitude while 50 VTEs including 4 PEs occurred at centers considered high altitude. The incidence of VTE at centers considered low altitude was 0.13%. The incidence of VTE at centers considered high altitude was 0.49%. The difference was statistically significant with a p-value <0.0001. The relative risk of developing a VTE was 3.8 times higher at high altitude. Conclusion: Patients undergoing arthroscopic procedures of the knee in cities located at high altitude are at higher risk of developing a VTE than those undergoing the same procedures at cities located at elevations near sea level.
机译:目的:本研究的目的是评估位于海拔附近海平面的手术中心进行膝关节镜手术的患者发生血栓栓塞事件的发生率,并将这些发生率与位于高城市的手术中心进行相同手术的患者进行比较高度。方法:使用主要医疗系统的数据库进行回顾性审查,该系统的医疗中心遍布美国。对15个州的115个手术中心进行了分析,分析了在2年的时间里接受过膝关节镜检查的患者的任何血栓栓塞事件,包括深静脉血栓形成(DVT)和肺栓塞(PE)。海拔低于1000英尺的手术中心被视为海平面中心。位于4000英尺以上海拔的那些中心被视为高海拔中心。海拔1000英尺至4000英尺之间的任何手术中心均不包括在内。结果:2011年至2012年之间,在低海拔中心对35,877例患者进行了膝关节镜检查。 2011年至2012年之间,有10181名患者在高海拔中心接受了膝关节镜检查。在同一时期内,总共有45个VTE,包括12个PE发生在被认为是低海拔的中心,而有50个VTE,包括4个PE发生在被认为是高海拔的中心。在被认为是低海拔的中心,VTE的发生率为0.13%。在被认为是高海拔的中心,VTE的发生率为0.49%。差异具有统计学意义,p值<0.0001。在高海拔地区,发生VTE的相对风险要高3.8倍。结论:在海拔较高的城市中,接受膝关节镜手术的患者发生VTE的风险高于在海拔较高的城市中进行相同手术的患者。

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