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Qualitative analysis of interviews of future non-affective psychotic disorder patients and non-psychiatric controls: preliminary results

机译:对未来非情感性精神病患者和非精神病患者进行访谈的定性分析:初步结果

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Background Previous research has shown that people with psychotic disorders have impaired functioning prior to the onset of the illness. The goal of this study is to obtain a detailed, in depth, analysis of the characteristics of premorbid impairment. Methods In this study we examined summaries of interviews with 20 male adolescents who were later diagnosed with non-affective psychotic disorders and compared them to interviews conducted with 20 matched controls without psychiatric disorders. The current study applied a qualitative analysis, performed in the following stages: each interview was read thoroughly by two blinded raters with no a-priori hypothesis, and then key themes and statements were identified and organized into meaningful domains. Afterwards, the frequency of each item was calculated and comparisons between the groups were performed. Results Future non-affective psychotic disorder patients were more likely to be described as strange or different, be involved in violent behavior, experience difficulties in educational functioning and peer integration, deal with problems in everyday functioning and have an avoidant interpersonal conflict resolution style in comparison with matched controls without psychiatric disorders. In addition, future patients experienced more stressful life events and dealt with these stressors more poorly in comparison with controls. Conclusions The findings of this unique historical-prospective qualitative analysis of interviews performed before the onset of psychosis, confirmed previous findings of premorbid abnormality of future non-affective psychosis patients. Using qualitative analysis enabled obtaining a more in-depth understanding of the real-life experience of the premorbid period among patients with non-affective psychotic disorders.
机译:背景技术先前的研究表明,精神病患者在疾病发作之前功能受损。这项研究的目的是获得对病前障碍特征的详细,深入的分析。方法在本研究中,我们检查了对后来被诊断出患有非情感性精神病的20名男性青少年的访谈摘要,并将其与对20名没有精神病的对照进行的访谈进行了比较。当前的研究应用了定性分析,该分析在以下阶段进行:两次访谈均由两名没有先验假设的盲目评估者彻底阅读,然后确定关键主题和陈述并将其组织到有意义的领域。之后,计算每个项目的频率并进行组间比较。结果未来的非情感性精神病患者更可能被描述为陌生或不同,参与暴力行为,在教育功能和同伴融合方面遇到困难,应对日常功能问题并且具有回避的人际冲突解决方式对照者没有精神病。此外,与对照组相比,未来的患者经历了更多的生活压力事件,并且对这些压力源的处理更加差。结论对精神病发作之前进行的访谈进行的这种独特的历史前瞻性定性分析结果,证实了先前对非情感性精神病患者病前异常的先前发现。使用定性分析可以使非情感性精神病患者更深入地了解病前期的现实生活。

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