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首页> 外文期刊>Schizophrenia research and treatment >Hospitalisation Utilisation and Costs in Schizophrenia Patients in Finland before and after Initiation of Risperidone Long-Acting Injection
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Hospitalisation Utilisation and Costs in Schizophrenia Patients in Finland before and after Initiation of Risperidone Long-Acting Injection

机译：利培酮长效注射开始和之后芬兰精神分裂症患者的住院使用和费用

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Objectives. Quantify changes in hospital resource use in Finland following initiation of risperidone long-acting injection (RLAI).Materials and Methods. A retrospective multi-center chart review (naturalistic setting) was used to compare annual hospital bed-days and hospital episodes for 177 schizophrenia patients (mean age 47.1 years, 52% female, 72% hospitalized) before and after initiation of RLAI (between January 2004 and June 2005) using the within-patient “mirror-image” study design. The base case analytical approach allocated hospital episodes overlapping the start date entirely to the preinitiation period. In order to investigate the impact of inpatient care ongoing at baseline, the change in bed-days was also estimated using an alternative analytical approached related to economic modelling.Results. In the conventional analysis, the mean annual hospitalisation costs declined by €11,900 and the number of bed-days was reduced by 40%, corresponding to 0.19 fewer hospital episodes per year. The reductions in bed-days per patient-year were similar for patients switched to RLAI as inpatients and as outpatients. In the modelling-based analysis, an 8% reduction in bed-days per year was observed.Conclusion. Despite uncertainty in the choice of analytic approach for allocating inpatient episodes that overlapping this initiation, consistent reductions in resource use are associated with the initiation of RLAI in Finland.
机译：目标。定量开始使用利培酮长效注射剂（RLAI）后芬兰医院资源使用的变化。材料和方法。回顾性多中心图表审查（自然环境）用于比较RLAI始发前后（1月之间）的177例精神分裂症患者（平均年龄47.1岁，女性52％，住院72％）的年度住院日数和医院发作次数。 （2004年和2005年6月）使用患者内的“镜像”研究设计。基本案例分析方法将医院发作分配为与开始日期完全重叠到预启动期间。为了调查基线时正在进行的住院护理的影响，还使用与经济建模相关的替代分析方法估算了卧床日的变化。在常规分析中，平均每年住院费用减少了11,900欧元，就诊天数减少了40％，相当于每年减少了0.19次医院发作。改用RLAI的患者与住院患者和门诊患者相比，每患者年减少卧床天数相似。在基于模型的分析中，观察到每年的卧床时间减少了8％。尽管在分配与该发作重叠的住院发作的分析方法选择方面存在不确定性，但芬兰的RLAI的发作与资源使用的持续减少有关。

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