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首页> 外文期刊>Sao Paulo Medical Journal >Prognostic factors in 291 patients with pulmonary metastases submitted to thoracotomy
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Prognostic factors in 291 patients with pulmonary metastases submitted to thoracotomy

机译：开胸手术的291例肺转移患者的预后因素

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Pulmonary metastases are among the most common sites for the spread of cancer, particularly with mesenchymal tumors. Despite improvements in cancer therapy, the prognosis remains poor, except for the highly selective group of patients who are considered eligible for surgical treatment and those with chemosensitive tumors. The main objective of this study was to evaluate survival results of 291 patients who underwent thoractomy due to pulmonary metastases between 1953 and 1986. The number of metastases ranged from a minimum of 1 to as many as 30. The type of resection depended on site, size, and number of pulmonary lesions: 154 wedge resections, 49 lobectomies, and 9 pneumectomies. The tumor was not resectable in the remaining 79 patients. Of the prognostic factors analyzed, only type of pulmonary resection (wedge vs. lobectomy vs. pneumectomy vs. unresectable) and disease free interval (DFI) between primary treatment and pulmonary metastases diagnosis ( 12 months) were selected as independent predictors of the risk of death in multivariate analysis. A reduced model for bone tumors included disease free interval, sex and histology.
机译：肺转移是最常见的癌症扩散部位，尤其是间充质肿瘤。尽管癌症治疗有所改善，但预后仍然很差，除了高度适合手术治疗的患者和具有化学敏感性肿瘤的患者。这项研究的主要目的是评估1953年至1986年间因肺转移而接受胸膜切开术的291例患者的生存结果。转移的数量范围从最少1到多达30个。切除的类型取决于部位，肺部病变的大小和数量：154例楔形切除，49例肺切除和9例肺切除。其余79例患者无法切除肿瘤。在分析的预后因素中，仅选择主要治疗和肺转移灶诊断之间（12个月）的肺切除类型（楔形，肺叶切除，肺切除术与不可切除）和无病间隔（DFI）作为独立的预测危险因素多因素分析中的死亡。骨肿瘤的简化模型包括无病间隔，性别和组织学。

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