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首页> 外文期刊>Sao Paulo Medical Journal >Overview of systematic reviews - a new type of study. Part II
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Overview of systematic reviews - a new type of study. Part II

机译：系统评价概述-一种新型的研究。第二部分

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CONTEXT AND OBJECTIVE: Overviews of Systematic Reviews (OoRs) are a new type of study in which multiple evidence from systematic reviews (SRs) is compiled into an accessible and useful document. The aim here was to describe the state of the art and critically assess Cochrane OoRs that have been published.DESIGN AND SETTING: Descriptive study conducted at a research center.METHODS: The OoRs identified through the filter developed in Part I of this study were evaluated in five domains: methodological quality; quality of evidence; implications for practice; general profile of OoRs; and length of work.RESULTS: All 13 OoRs included had high methodological quality. Some OoRs did not present sufficient data to judge the quality of evidence; using sensitivity analysis, the quality of evidence of the OoRs increased. Regarding implications for practice, 64% of the interventions were judged as beneficial or harmful, while 36% of them showed insufficient evidence for judgment. It is expected (with 95% confidence interval) that one OoR will include 9,462 to 64,469 patients, 9 to 29 systematic reviews and 80 to 344 primary studies, and assess 6 to 21 interventions; and that 50 to 92% of OoRs will produce meta-analysis. The OoRs generated 2 to 26 meta-analyses over a period of 18 to 31 months.CONCLUSION: The OoRs presented high methodological quality; the quality of evidence tended to be moderate/high; most interventions were judged to be beneficial/harmful; the mean length of work was 24 months. The OoR profile adds power to decision-making.
机译：内容与目的：系统评价（OoR）概述是一种新型研究，其中系统评价（SR）的多个证据被汇编成易于访问且有用的文档。目的是描述技术水平并严格评估已发表的Cochrane OoR。设计与设置：在研究中心进行的描述性研究方法：通过本研究第一部分开发的过滤器对OoR进行评估在五个领域：方法论质量;证据质量;对实践的影响; OoR的概况;结果：纳入的所有13个OoR均具有较高的方法学质量。一些OoR没有提供足够的数据来判断证据的质量;使用敏感性分析，OoR的证据质量提高了。关于对实践的影响，有64％的干预措施被判定为有益或有害，而其中36％的干预措施证据不足。预计（以95％的置信区间）一个OoR将包括9,462至64,469例患者，9至29个系统评价和80至344个主要研究，并评估6至21个干预措施;而且有50％到92％的OoR会进行荟萃分析。在18到31个月的时间内，OoR生成了2到26项荟萃分析。证据质量趋于中等/高;大多数干预措施被认为是有益/有害的;平均工作时间为24个月。 OoR配置文件增强了决策制定能力。

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