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首页> 外文期刊>Sao Paulo Medical Journal >Clinical and laboratorial features of spontaneous bacterial peritonitis in southern Brazil
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Clinical and laboratorial features of spontaneous bacterial peritonitis in southern Brazil

机译：巴西南部自发性细菌性腹膜炎的临床和实验室特征

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CONTEXT AND OBJECTIVE: Spontaneous bacterial peritonitis (SBP) is a severe complication that occurs in 8-27% of hospitalized patients with liver cirrhosis and ascites, with high mortality rates. This study aimed to identify the clinical characteristics associated with SBP.DESIGN AND SETTING: Cross-sectional study, conducted in a public university.METHODS: The study consecutively included individuals with liver cirrhosis and ascites between September 2009 and March 2012. Forty-five patients were included: mean age 53.2 ± 12.3 years, 82.2% male, 73.8% Caucasian, mean Model of End-stage Liver Disease (MELD) score of 19.5 ± 7.2, and 33.3% with SBP. The subjects were divided into two groups: SBP and controls.RESULTS: Comparison between individuals with SBP and controls showed that those with SBP had lower mean prothrombin activity time (36.1 ± 16.0% versus 47.1 ± 17.2%; P = 0.044) and lower median serum-ascites albumin gradient (SAAG) (1.2 versus 1.7, P = 0.045). There was a tendency towards higher mean MELD in the SBP group, not significant (22.2 ± 7.6 versus 17.9 ± 6.7; P = 0.067). There was a strong positive correlation between the neutrophil count in ascitic fluid and serum leukocyte count (r = 0.501; P = 0.001) and a negative correlation between the neutrophil count in ascitic fluid with prothrombin activity time (r = -0.385; P = 0.011).CONCLUSION: A few characteristics are associated with the presence of SBP, especially liver dysfunction, SAAG and peripheral leukocytosis.
机译：背景与目的：自发性细菌性腹膜炎（SBP）是一种严重并发症，发生在住院的肝硬化和腹水患者中，占8-27％，死亡率很高。这项研究旨在确定与SBP相关的临床特征。设计与设置：在公立大学进行的横断面研究。方法：该研究在2009年9月至2012年3月期间连续纳入肝硬化和腹水患者。45例患者包括：平均年龄53.2±12.3岁，男性82.2％，白种人73.8％，平均终末期肝病模型（MELD）评分为19.5±7.2，SBP评分为33.3％。结果：SBP个体与对照组之间的比较显示，SBP个体与凝血酶原的平均活动时间较低（36.1±16.0％vs 47.1±17.2％; P = 0.044），中位数较低血清-腹水白蛋白梯度（SAAG）（1.2对1.7，P = 0.045）。 SBP组有较高的平均MELD趋势，但不显着（22.2±7.6对17.9±6.7; P = 0.067）。腹水中的中性粒细胞计数与血清白细胞计数之间呈强正相关（r = 0.501; P = 0.001），而腹水中的中性粒细胞计数与凝血酶原活性时间呈负相关（r = -0.385; P = 0.011）结论：SBP的存在与一些特征有关，尤其是肝功能障碍，SAAG和外周血白细胞增多。

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