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Clinical and epidemiological profile of tuberculosis in an urban area with high human development index in southeastern Brazil. Time series study

机译:在巴西东南部人类发展指数高的城市地区,结核病的临床和流行病学特征。时间序列研究

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ABSTRACT CONTEXT AND OBJECTIVE: In the twenty-first century, tuberculosis remains a serious public health problem in Brazil. The aim here was to characterize tuberculosis in a municipality with a high human development index (HDI), based on clinical and epidemiological variables. DESIGN AND SETTING: Epidemiological study with analysis of incidence that included 533 new cases of tuberculosis in the municipality of Araraquara, S?o Paulo, reported to the Brazilian Notifiable Diseases Information System (SINAN) between 2002 and 2011. METHODS: To identify trends, this period was divided into two five-year periods (2002-2006 and 2007-2011). The incidence rates were compared using ratios and confidence intervals. RESULTS: The incidence of tuberculosis was 26.82 cases per 100,000 inhabitants, and decreased by 22% between the two periods, which was statistically significant. Cases were more prevalent among men (72.61%) and among adults between 30 and 59 years of age with non-specialized professions and low education levels. There was a statistically significant reduction in cases among individuals over 50. The age group with highest incidence was 50-59 years in the first period and 30-39 years in the second. Total recovery occurred in more than 70%. There was a reduction in the number of diagnoses made within primary care and an increase within public hospital care between the two periods. The most common coinfections were AIDS and hepatitis C. CONCLUSIONS: The incidence of tuberculosis in this municipality was lower than the national incidence, with a declining trend and a high cure rate, and the main coinfections were AIDS and hepatitis C.
机译:摘要背景和目的:在二十一世纪,结核病在巴西仍然是一个严重的公共卫生问题。此处的目的是根据临床和流行病学变量,对人类发展指数(HDI)高的城市进行结核病特征分析。设计与地点:流行病学研究及其发病率分析,包括2002年至2011年间向巴西法定传染病信息系统(SINAN)报告的圣保罗Araraquara市533例结核病新病例。方法:确定趋势,这个时期分为两个五年期(2002-2006年和2007-2011年)。使用比率和置信区间比较了发病率。结果:结核病的发病率为每10万居民26.82例,在两个时期之间下降了22%,具有统计学意义。男性(72.61%)和30-59岁的非专业职业和低文化程度的成年人中,这种情况更为普遍。在50岁以上的人群中,病例数有统计上的显着下降。发病率最高的年龄组在第一个时期为50-59岁,在第二个时期为30-39岁。总回收率超过70%。在这两个时期之间,初级保健中的诊断数量有所减少,而公立医院中的诊断数量有所增加。结论:本市的结核病发病率低于全国发病率,呈下降趋势,治愈率较高,主要合并感染为艾滋病和丙型肝炎。

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