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Prognosis related to staging systems for chronic lymphocytic leukemia

机译:与慢性淋巴细胞白血病分期系统有关的预后

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CONTEXT: Chronic lymphocytic leukemia (CLL) is a clonal lymphoproliferative disorder, characterized by B lymphocytic proliferation. CLL is the most frequent adult leukemia in Western countries, accounting for 25 to 30% of all white leukemic patients. OBJECTIVE: To evaluate clinical and staging characteristics in prognosis of chronic lymphocytic leukemia. DESIGN: Evaluation of clinical-staging data. SETTING: Universidade Federal de S?o Paulo - Escola Paulista de Medicina / Universidade de Alfenas. SAMPLE: 73 patients diagnosed from 1977 to 1994. MAIN MEASUREMENTS: Sex, ethnic origin, age, lymphadenopathy, splenomegaly, hepatomegaly, three or more areas of lymphoid enlargement, hemoglobin (g/dl), lymphocytes/mm3, Platelets/mm3 RESULTS: Mean survival of patients was 76 months, median age was 65 years, ranging from 33 to 87. Forty-four patients (60.3%) were male and 29 (39.7%) female. CONCLUSION: The Binet system determined a better prognosis than Rai.
机译:背景:慢性淋巴细胞性白血病(CLL)是一种克隆性淋巴细胞增生性疾病,其特征是B淋巴细胞增殖。 CLL是西方国家最常见的成人白血病,占所有白人白血病患者的25%至30%。目的:评价慢性淋巴细胞白血病的临床及分期特征。设计:评估临床分期数据。地点:圣保罗州立大学-埃斯科拉·保利斯塔·德·梅迪西纳/阿尔芬那大学。样本:1977年至1994年诊断为73例患者。主要测量指标:性别,种族,年龄,淋巴结病,脾肿大,肝肿大,淋巴结肿大三个或更多区域,血红蛋白(g / dl),淋巴细胞/ mm3,血小板/ mm3结果:患者的平均生存期为76个月,中位年龄为65岁,范围从33至87。男性为44例(60.3%),女性为29例(39.7%)。结论:Binet系统预后比Rai好。

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