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Latent Autoimmune Diabetes of the Adult (LADA) in a Brazilian Indian

机译:巴西印第安人的成人潜在自身免疫性糖尿病(LADA)

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CONTEXT: Latent autoimmune diabetes of the adult (LADA) as originally described represents perhaps as many as 10 -- 20% of adult-onset patients with diabetes. DESIGN: case report. CASE REPORT: A 38-year-old Brazilian Xavante-Jê Indian with Latent Autoimmune Diabetes of the Adult (LADA) is described, coming from the Sangradouro community in Poxoréu, Mato Grosso. The onset of diabetes after reaching 25 years of age, the evolution to insulin deficiency after a period of insulin-independence and the presence of auto-antibodies to glutamic acid decarboxylase (GAD) characteristic of LADA were present. This patient may represent the first case of LADA in a Brazilian with full Indian heritage. Further studies are necessary to verify the prevalence of this new type of diabetes in this population that does not have Caucasoid admixture and has a particular environmental background.
机译:背景:最初描述的成人潜伏性自身免疫性糖尿病(LADA)可能占成年人发病的糖尿病患者的10%至20%。设计:病例报告。病例报告:一名来自马托格罗索州Poxoréu的Sangradouro社区描述了一名38岁的巴西成人潜在自身免疫性糖尿病(XADA)的巴西Xavante-Jê印第安人。出现了25岁以后的糖尿病发作,一段时间的胰岛素独立后演变为胰岛素缺乏症和LADA的特征性谷氨酸脱羧酶(GAD)自身抗体的情况。该患者可能代表了具有完整印度血统的巴西人中的LADA第一例。有必要进行进一步的研究来验证这种新型糖尿病在这种人群中的流行,这种人群没有高加索混合物,并且具有特殊的环境背景。

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