...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Sao Paulo Medical Journal >Uterine artery embolization for the treatment of symptomatic myomas in Brazilian women
【24h】

Uterine artery embolization for the treatment of symptomatic myomas in Brazilian women

机译：子宫动脉栓塞术治疗巴西女性症状性肌瘤

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

CONTEXT: Uterine myomas are benign tumors that mostly occur in women of reproductive age at a frequency ranging from 20 to 25%. The symptoms are increased menstrual flow, pain and compressive signs. New treatments have been proposed and uterine artery embolization is one of them. OBJECTIVE: To evaluate the effects of treatment by embolization of the uterine artery, in women with symptomatic myomas. Uterine and dominant myoma volumes and the major symptoms were evaluated before treatment and 12 weeks later. TYPE OF STUDY: Open clinical trial. SETTING: A tertiary-care women's hospital. PARTICIPANTS: The study was conducted on 32 women with symptomatic single or multiple myomas of the uterine body, seen at the outpatient unit from May 2000 to September 2001. MAIN MEASUREMENTS: The patients were submitted to gynecological examination and abdominal and endovaginal pelvic ultrasonography, and the examinations were repeated 12 weeks after the first procedure. Uterine artery embolization using PVA (polyvinyl alcohol) particles of 355-700 μ was performed by catheterization of the right femoral artery in 30 women and by bilateral catheterization in two. RESULTS: Before embolization, the mean uterine volume of the 32 women was 455 cm3 and the mean volume of the dominant myoma was 150 cm3. Twelve weeks after embolization, the mean uterine volume was 256 cm3 and the mean volume of the dominant myoma was 91 cm3, with p < 0.01 in both cases. Twelve weeks after the treatment, all the women answered a questionnaire, which showed that 71% had improvement in menstrual regularity, 90% decreased menstrual volume and 81% shortened menstrual duration. The most frequent immediate post-procedure symptoms, established as complications, were pain (100%) and fatigue (34%). One woman had myoma degeneration and was submitted to myomectomy. CONCLUSION: The significant reduction in uterine and dominant myoma volume confirms the validity of the treatment of symptomatic myomas by the technique of uterine artery embolization in Brazilian women. There was significant reduction in menstrual flow and duration, as well as better cycle regularity in the women studied. The few adverse effects observed in the sample studied mainly involved pain immediately after embolization.
机译：背景：子宫肌瘤是良性肿瘤，多发于育龄妇女，发病率在20％到25％之间。症状是月经量增加，疼痛和压迫症状。已经提出了新的治疗方法，子宫动脉栓塞术就是其中之一。目的：评价有症状的肌瘤女性通过子宫动脉栓塞治疗的效果。在治疗前和12周后评估子宫和优势肌瘤的体积以及主要症状。研究类型：开放式临床试验。地点：一家三级保健妇女医院。参加者：该研究是针对2000年5月至2001年9月在门诊就诊的32例有症状的子宫体单发或多发子宫肌瘤的妇女进行的。主要测量指标：对患者进行了妇科检查以及腹部和阴道阴道盆腔超声检查，以及在第一次手术后12周重复检查。通过对30例女性的右股动脉进行导管插入术以及对两名女性进行双侧导管插入术，使用355-700μm的PVA（聚乙烯醇）颗粒进行子宫动脉栓塞术。结果：在栓塞术前，这32名妇女的平均子宫体积为455 cm3，而优势肌瘤的平均体积为150 cm3。栓塞后十二周，子宫平均体积为256 cm3，优势肌瘤的平均体积为91 cm3，两种情况下的p <0.01。治疗后十二周，所有妇女均回答了问卷，结果表明71％的女性月经规律有所改善，90％的女性月经量减少，81％的女性经期缩短。确定为并发症的最常见的手术后立即症状是疼痛（100％）和疲劳（34％）。一名妇女患有肌瘤变性，并接受了子宫肌瘤切除术。结论：子宫和显性肌瘤体积的明显减少证实了通过子宫动脉栓塞技术治疗巴西女性症状性肌瘤的有效性。在研究的女性中，月经量和持续时间显着减少，并且周期规律性更好。在研究的样品中观察到的少数不良反应主要涉及栓塞后立即疼痛。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号