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首页> 外文期刊>Sao Paulo Medical Journal >A 12-month follow-up of an influenza vaccination campaign based on voluntary adherence: report on upper-respiratory symptoms among volunteers and non-volunteers
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A 12-month follow-up of an influenza vaccination campaign based on voluntary adherence: report on upper-respiratory symptoms among volunteers and non-volunteers

机译：基于自愿遵守的流感疫苗接种运动的12个月跟踪：关于志愿者和非志愿者的上呼吸道症状的报告

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CONTEXT: Routine immunization of groups at high risk for influenza has been progressively implemented as a matter of Brazilian public health policy. Although the benefits of the vaccination for healthy young adults are still controversial, it has been offered yearly to hundreds of thousands of Brazilian workers, generally as part of wellness initiatives in the workplace. OBJECTIVE: To study the characteristics of subjects that accepted or refused to be vaccinated against influenza and to report on respiratory symptoms in both groups, one year after the campaign date. DESIGN: A prospective observational study. SETTING: Workers at a subsidiary of an international bank in S?o Paulo, Brazil. PARTICIPANTS: 124 persons that did not accept and 145 that voluntarily accepted the vaccine completed 12 months of follow-up. MAIN MEASUREMENTS: Data concerning gender, age, tobacco use, and any history of chronic respiratory illness such as asthma, bronchitis, rhinitis, and repetitive upper-respiratory infections, were recorded at the time of vaccination. After that, workers were asked monthly by questionnaire or telephone about respiratory symptoms, days of work lost and medical consultations. RESULTS: The results showed statistically significant differences regarding age (P = 0.004) with the vaccinated group (V) being younger than the non-vaccinated (NV) one, and with reference to previous repetitive upper-respiratory infections being higher among the V group (P < 0.0001). During the follow-up, the V group reported more occurrences of upper respiratory symptoms (P < 0.0001), due to both non-influenza (P < 0.0001) and influenza-like illness (P = 0.045). Differences were also found between V and NV groups concerning days off work and number of medical consultations due to upper-respiratory symptoms and non-influenza illness. Gender and history of repetitive upper-respiratory infections were the best predictors of influenza-like illness-related events. CONCLUSIONS: The making of previous reference to repetitive upper-respiratory infections was a major difference between those who accepted or rejected the vaccine. The vaccination itself was not sufficient to reduce the number of occurrences of respiratory symptoms and related absenteeism to levels similar to those found among non-vaccinated people.
机译：背景：根据巴西的公共卫生政策，对流感高危人群的常规免疫已逐步实施。尽管对于健康的年轻人来说，接种疫苗的好处仍存在争议，但通常作为工作场所健康计划的一部分，每年向成千上万的巴西工人提供这种疫苗。目的：研究在运动日期后一年接受或拒绝接受流感疫苗接种的受试者的特征，并报告两组的呼吸道症状。设计：一项前瞻性观察研究。地点：巴西圣保罗一家国际银行子公司的工人。参与者：124名不接受疫苗的人和145名自愿接受疫苗的人完成了12个月的随访。主要测量指标：接种疫苗时记录有关性别，年龄，烟草使用以及任何慢性呼吸道疾病史（如哮喘，支气管炎，鼻炎和反复性上呼吸道感染）的数据。之后，每月通过问卷或电话询问工人呼吸道症状，工作日数和医疗咨询。结果：结果显示，接种组（V）的年龄比未接种组（NV）的年龄小（P = 0.004），且在V组中以前的重复性上呼吸道感染较高，差异有统计学意义（P = 0.004）。 （P <0.0001）。在随访期间，V组报告由于非流感（P <0.0001）和类流感样疾病（P = 0.045）导致更多的上呼吸道症状发生（P <0.0001）。在V和NV组之间，由于上呼吸道症状和非流感疾病，在休假天数和就诊次数方面也存在差异。性别和重复性上呼吸道感染史是流感样疾病相关事件的最佳预测因子。结论：先前提到的重复性上呼吸道感染是接受或拒绝该疫苗的人之间的主要区别。疫苗接种本身不足以将呼吸道症状和相关旷工的发生率降低到与未接种疫苗的人类似的水平。

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