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Pattern of patch test reactivity among patients with clinical diagnosis of contact dermatitis: A hospital-based study

机译：临床诊断为接触性皮炎的患者的斑贴试验反应性模式：一项基于医院的研究

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Introduction: The patterns of positive patch test in Nepal have not been defined so far. The aim of this studywas to describe the patterns of patch test reactivity in suspected Allergic Contact Dermatitis (ACD) patients.Methods: This was a hospital based retrospective study performed to investigate patch test reactivity in patientswith ACD from April, 2016 through October, 2016. The data of patients who underwent patch test during thisperiod were extracted and analyzed. Results: A total of 35 patients were included in the study. Nineteen (54.3%)tested positive to either one or more allergens. Among them, 17 (89.4%) reacted positively to a single allergen.The following patterns of positives were seen: nickel sulfate, 5 (26.3%), fragrance mix 3 (15.7%), and parthenium3 (15.7%). Cobalt sulfate, formaldehyde, potassium dichromate, benzocaine, nitrofurazone, chlorocresol each waspositive in single patient. Majority of the patients were housewives (22.6%) followed by students and officers (13%each), farmers (10%), health care workers (9.7%), wet work (6.5%) and others (20). Less than half (45%) of thehand eczema showed positive patch test. Similarly,40% of the patient of scattered generalized dermatitis showedreactivity to parthenium, nickel sulfate and multiple antigens. Conclusions: The most common allergens identifiedwere nickel sulfate, fragrance mix and parthenium. Since, there is no well defined contact allergen in the Nepalesecommunity, so patch test kits developed elsewhere might not have been beneficial and calls for need of large scaleinvestigation to identify the local allergens.
机译：简介：尼泊尔目前尚未确定阳性斑块测试的模式。这项研究的目的是描述疑似过敏性接触性皮炎（ACD）患者的斑贴试验反应模式。方法：这是一项基于医院的回顾性研究，旨在调查2016年4月至2016年10月间ACD患者的斑贴试验反应性。提取并分析在此期间接受斑贴试验的患者的数据。结果：总共35名患者被纳入研究。 19种（54.3％）对一种或多种过敏原呈阳性。其中，有17种（89.4％）对单一过敏原呈阳性反应，观察到以下阳性模式：硫酸镍，5种（26.3％），混合香料3（15.7％）和Parthenium3（15.7％）。硫酸钴，甲醛，重铬酸钾，苯佐卡因，呋喃酮，氯甲酚在单个患者中均为阳性。患者的大多数是家庭主妇（22.6％），其次是学生和官员（每人13％），农民（10％），医护人员（9.7％），湿工作（6.5％）和其他人（20）。不到一半（45％）的手湿疹显示出阳性的斑贴试验。同样，散在的全身性皮炎患者中有40％表现出对单性hen，硫酸镍和多种抗原的反应性。结论：鉴定出的最常见的过敏原为硫酸镍，香料混合物和单性part。由于尼泊尔社区中没有明确定义的接触性过敏原，因此在其他地方开发的贴片检测试剂盒可能没有用，因此需要进行大规模调查以鉴定当地过敏原。

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