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首页> 外文期刊>Sao Paulo Medical Journal >Epidemiological and serological aspects of hepatitis A among children and teenagers in the city of Santos: a cross-sectional study
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Epidemiological and serological aspects of hepatitis A among children and teenagers in the city of Santos: a cross-sectional study

机译：桑托斯市儿童和青少年中甲型肝炎的流行病学和血清学方面：一项横断面研究

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CONTEXT AND OBJECTIVE: Viral hepatitis A is still a concern at public health level in Brazil and around the world, due both to the number of affected subjects and the possibility of complications in the acute forms. The Brazilian Ministry of Health estimates that at least 70% of this country's population has already had contact with the hepatitis A virus (HAV). The aim here was to discover the prevalence of serological markers for the hepatitis A virus among children and teenagers at daycare facilities, kindergartens and elementary schools in the city of Santos. DESIGN AND SETTING: Cross-sectional study in kindergartens and elementary schools within the municipal education network in several regions of the city of Santos. METHOD: Students' family members were surveyed using a questionnaire and 4,680 finger-prick blood samples were taken and assayed by means of the ELISA technique. RESULTS: The general prevalence of anti-HAV IgG was 9.72% and, of these cases, 74.6% were reactive to anti-HAV IgM. There was higher prevalence of anti-HAV IgG among older children, females, children who played in streams, those whose homes were not connected to the sewage system, those whose parents had low education levels, those with low household income and those who did not live along the seashore. The prevalence of anti-HAV IgM peaked in the early years and subsequently fell, and it was lower on the hills and in the Northwestern Zone. CONCLUSION: The general prevalence of serological markers for hepatitis A was low in Santos.
机译：背景与目的：由于受影响对象的数量以及急性形式的并发症的可能性，在巴西和世界范围内，甲型病毒性肝炎仍然是公共卫生方面的关注重点。巴西卫生部估计，该国至少70％的人口已经接触过甲型肝炎病毒（HAV）。目的是在桑托斯市的托儿所，幼儿园和小学中，发现儿童和青少年中甲型肝炎病毒血清学标志物的流行情况。设计与环境：在桑托斯市多个地区的市政教育网络内的幼儿园和小学中进行横断面研究。方法：使用问卷对学生的家庭成员进行调查，并通过ELISA技术对4,680例手指刺血样本进行分析。结果：抗HAV IgG的普遍患病率为9.72％，其中74.6％对抗HAV IgM有反应。在年龄较大的儿童，女性，在河里嬉戏的儿童，家庭与污水处理系统不相连的儿童，父母的文化程度低，家庭收入低的儿童和没有家庭的儿童中，抗HAV IgG的患病率较高。住在海边。抗HAV IgM的发生率在早期达到高峰，然后下降，在丘陵和西北地区则较低。结论：桑托斯地区甲型肝炎的血清学标志物普遍存在。

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