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首页> 外文期刊>Sao Paulo Medical Journal >Calcium renal lithiasis: metabolic diagnosis and medical treatment
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Calcium renal lithiasis: metabolic diagnosis and medical treatment

机译：钙肾结石：代谢诊断和药物治疗

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Calcium renal lithiasis is a frequent condition that affects the worldwide population and has a high recurrence rate. Different metabolic changes may trigger the onset of calcium stone disorders, such as hypercalciuria, hyperoxaluria, hyperuricosuria, hypocitraturia and others. There are also other very prevalent disorders that are associated with calcium calculi, such as arterial hypertension, obesity and loss of bone mineral density. A correct diagnosis needs to be obtained through examining the serum and urinary parameters of mineral metabolism in order to carry out adequate prevention and treatment of this condition. Once the metabolic diagnosis is known, it is possible to establish dietary and pharmacological treatment that may enable monitoring of the disease and prevent recurrence of stone formation. Some advances in treating this pathological condition have been made, and these include use of sodium alendronate in patients with calcium renal lithiasis and osteopenia/osteoporosis, or use of a combination of a thiazide with a bisphosphonate. In summary, calcium renal lithiasis often requires multidrug treatment with strict control and follow-up of patients.
机译：钙肾结石是一种常见病，会影响全世界的人群并且复发率很高。不同的代谢变化可能会触发钙结石疾病的发作，例如高钙尿症，高草酸尿症，尿酸尿过多，低尿酸症等。还存在与钙结石有关的其他非常普遍的疾病，例如动脉高血压，肥胖症和骨矿物质密度损失。需要通过检查矿物质代谢的血清和尿参数来获得正确的诊断，以便对此病进行充分的预防和治疗。一旦知道了代谢诊断，就有可能建立饮食和药理学治疗方法，以监测疾病并防止结石复发。已经在治疗这种病理状况方面取得了一些进展，其中包括在患有肾结石钙化和骨质疏松/骨质疏松症的患者中使用阿仑膦酸钠，或使用噻嗪类与双膦酸盐的组合。总之，肾结石钙化经常需要严格控制和随访患者的多种药物治疗。

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