a-Interferon therapy for HBV-related glomerulonephritis

Antonio Eduardo Benedito Silva; Cibele Nascimento Cruz; Edmundo Pessoa De Almeida Lopes Neto; Gianna Mastroianni Kirsztajn; Lucila Valente Lopes; Maria Lucia Gomes Ferraz

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a-Interferon therapy for HBV-related glomerulonephritis

机译：α-干扰素治疗HBV相关性肾小球肾炎

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We report a case of a patient with hepatitis B virus (HBV)-related membranous glomerulonephritis (MGN) who showed improvement after interferon-a (IFN-a) therapy. A 35-year-old man with nephrotic syndrome and HBV antigens received a 24-week course of IFN-a. At the end of therapy there was an elevation in the level of plasma aminotransferase and an increase in proteinuria, which were followed by antigen/antibody seroconversion. This "flare-up" before seroconversion suggests an increase in disease activity in the liver and kidney, demonstrating in vivo HBV involvement in MGN.

机译：我们报告了一例患有乙型肝炎病毒（HBV）相关性膜性肾小球肾炎（MGN）的患者，该患者在干扰素- a （IFN- a ）治疗。一名患有肾病综合征和HBV抗原的35岁男子接受了为期24周的IFN- a 治疗。在治疗结束时，血浆氨基转移酶水平升高，蛋白尿增加，随后是抗原/抗体血清转化。血清转化之前的这种“发作”表明肝脏和肾脏中疾病活动的增加，表明体内HBV参与了MGN。

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《Sao Paulo Medical Journal》 |1998年第5期|共3页
作者
Antonio Eduardo Benedito Silva; Cibele Nascimento Cruz; Edmundo Pessoa De Almeida Lopes Neto; Gianna Mastroianni Kirsztajn; Lucila Valente Lopes; Maria Lucia Gomes Ferraz;
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中图分类临床医学;
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1. Remission of HBV-related mesangioproliferative glomerulonephritis after interferon therapy. [J] . Dhiman RK, Kohli HS, Das G, Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association - European Renal Association . 1999,第1期

机译：干扰素治疗后HBV相关性血管增生性肾小球肾炎的缓解。
2. Replication and infectivity of hepatitis B virus in HBV-related glomerulonephritis. [J] . Chen L, Wu C, Fan X International journal of infectious diseases: IJID : official publication of the International Society for Infectious Diseases . 2009,第3期

机译：乙型肝炎病毒在HBV相关性肾小球肾炎中的复制和感染性。
3. Replication and infectivity of hepatitis B virus in HBV-related glomerulonephritis [J] . Lizhang Chen, Chengqiu Wu, Xuegong Fan, International journal of infectious diseases : . 2009,第3期

机译：乙型肝炎病毒在乙肝相关性肾小球肾炎中的复制和感染性
4. Multiagent-Based Simulation of the Human Immune System: A Study of the Immune Response and Antimicrobial Therapy in Post-Streptococcal Glomerulonephritis [C] . Carlos Antonio Bastos, Alcione de Paiva Oliveira, Fabio Ribeiro Cerqueira, International Florida Aritificial Intelligence Research Society Conference . 2016

机译：基于多元素的人免疫系统模拟 - 后肽肾小球肾炎药中免疫应答和抗菌治疗研究
5. Analysis of the complexity of HBV-host junction sequences in patients with HBV-related hepatocellular carcinoma [D] . Lin, Selena 2016

机译：乙肝相关肝细胞癌患者乙肝病毒宿主连接序列的复杂性分析
6. The clinical efficacy and adverse effects of Entecavir plus Thymosin alpha-1 combination therapy versus Entecavir Monotherapy in HBV-related cirrhosis: a systematic review and meta-analysis [O] . Dan Peng, Hai-Yan Xing, Chen Li, 2020

机译：恩替卡韦拉胸腺素α-1组合治疗对HBV相关性肝硬化的临床疗效和不良反应：系统评价和荟萃分析
7. a-Interferon therapy for HBV-related glomerulonephritis [O] . Edmundo Pessoa de Almeida Lopes Neto, Lucila Valente Lopes, Gianna Mastroianni Kirsztajn, 1998

机译： a - 干扰素治疗HBV相关性肾小球肾炎

a-Interferon therapy for HBV-related glomerulonephritis

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