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首页> 外文期刊>Sao Paulo Medical Journal >Relationship between blood donors' iron status and their age, body mass index and donation frequency
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Relationship between blood donors' iron status and their age, body mass index and donation frequency

机译：献血者铁水平与年龄，体重指数和献血频率之间的关系

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CONTEXT AND OBJECTIVE: Regular blood donation may decrease body iron storage and lead to anemia. The aim here was to evaluate the iron status of Iranian male blood donors and the impact of age, body mass index (BMI) and donation frequency over one year, on iron status indices. DESIGN AND SETTING: Cross-sectional, descriptive and analytical study at Tehran Blood Transfusion Center, Tehran, Iran. METHODS: Between July and September 2011, 117 male blood donors were selected and divided into four groups according to their frequency of blood donation. Thirty male non-donors were also recruited as controls after adjusting for age, weight, height, smoking habits and monthly income. Iron status indices and some criteria such as general health and dietary measurements were determined among all subjects. RESULTS: The values of the iron-related parameters were significantly lower among donors than among non-donors. Only total iron binding capacity (TIBC) was found to be significantly higher among different donor groups than in the controls. A significant positive correlation was observed between age and serum ferritin (SF) only among the donors who had donated once within the preceding year. The iron status indices did not show any significant relationship with BMI among donors or non-donors. CONCLUSION: A donation frequency of more than twice a year had a significant influence on iron-related parameters. Therefore, without annual measurement of these parameters, further phlebotomies may lead to iron deficiency and donor rejection in the future.
机译：背景与目的：定期献血可能会减少体内铁的储存并导致贫血。这里的目的是评估伊朗男性献血者的铁状况以及年龄，体重指数（BMI）和一年以上的献血频率对铁状况指数的影响。设计与设置：在伊朗德黑兰德黑兰输血中心进行的横断面，描述性和分析性研究。方法：选择2011年7月至9月的117名男性无偿献血者，根据其献血频率将其分为四组。在调整了年龄，体重，身高，吸烟习惯和月收入之后，还招募了三十名男性非捐献者作为对照。在所有受试者中确定铁状态指数和一些标准，例如总体健康和饮食测量。结果：供体中铁相关参数的值显着低于非供体中。发现不同供体组之间的总铁结合能力（TIBC）明显高于对照组。仅在前一年内捐献一次的捐献者中，年龄和血清铁蛋白（SF）之间存在显着的正相关。铁状态指数与供体或非供体之间的体重指数没有显着关系。结论：每年两次以上的捐赠频率对铁相关参数有重大影响。因此，如果不对这些参数进行年度测量，将来进行静脉放血可能会导致铁缺乏和供体排斥。

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