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What do Cochrane systematic reviews say about non-pharmacological interventions for treating cognitive decline and dementia?

机译:Cochrane系统评价对治疗认知下降和痴呆的非药物干预措施有何看法?

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BACKGROUND: Dementia is a highly prevalent condition worldwide. Its chronic and progressive presentation has an impact on physical and psychosocial characteristics and on public healthcare. Our aim was to summarize evidence from Cochrane reviews on non-pharmacological treatments for cognitive disorders and dementia. DESIGN AND SETTING: Review of systematic reviews, conducted in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina, Universidade Federal de S?£o Paulo. METHODS: Cochrane reviews on non-pharmacological interventions for cognitive dysfunctions and/or type of dementia were included. For this, independent assessments were made by two authors. RESULTS: Twenty-four reviews were included. These showed that carbohydrate intake and validation therapy may be beneficial for cognitive disorders. For dementia, there is a potential benefit from physical activity programs, cognitive training, psychological treatments, aromatherapy, light therapy, cognitive rehabilitation, cognitive stimulation, hyperbaric oxygen therapy in association with donepezil, functional analysis, reminiscence therapy, transcutaneous electrical stimulation, structured decision-making on feeding options, case management approaches, interventions by non-specialist healthcare workers and specialized care units. No benefits were found in relation to enteral tube feeding, acupuncture, Snoezelen stimulation, respite care, palliative care team and interventions to prevent wandering behavior. CONCLUSION: Many non-pharmacological interventions for patients with cognitive impairment and dementia have been studied and potential benefits have been shown. However, the strength of evidence derived from these studies was considered low overall, due to the methodological limitations of the primary studies.
机译:背景:痴呆症是世界范围内高度流行的疾病。它的慢性和进行性表现会影响身体和心理社会特征以及公共保健。我们的目的是总结Cochrane评论中关于认知障碍和痴呆的非药物治疗的证据。设计与环境:系统评价的回顾,在循证医学学科,圣保罗大学联邦医学院的Escola Paulista de Medicina进行。方法:包括关于认知功能障碍和/或痴呆类型的非药物干预的Cochrane评价。为此,两位作者进行了独立评估。结果:纳入二十四条评论。这些表明碳水化合物的摄入和验证疗法可能对认知障碍有益。对于痴呆症,体育锻炼计划,认知训练,心理治疗,芳香疗法,光疗,认知康复,认知刺激,高压氧疗法与多奈哌齐联合使用,功能分析,回忆疗法,经皮电刺激,结构化决策可能会带来潜在的好处-制定喂养方案,病例管理方法,非专科医护人员和专科病房的干预措施。没有发现与肠管饲喂,针灸,Sneozelen刺激,暂托,姑息治疗小组和预防流浪行为的干预有关的益处。结论:已经研究了许多针对认知障碍和痴呆患者的非药物干预措施,并显示出潜在的益处。然而,由于基础研究的方法学局限性,这些研究得出的证据总体上被认为是低下的。

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