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首页> 外文期刊>Sao Paulo Medical Journal >Lymphocele: a possible relationship with acute cellular rejection in kidney transplantation
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Lymphocele: a possible relationship with acute cellular rejection in kidney transplantation

机译：淋巴球肿：与肾移植中急性细胞排斥反应的可能关系

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CONTEXT: The incidence of lymphocele after renal transplantation varies between 0.6 and 18% of cases, and many factors have been associated to its etiology. Cellular rejection of the kidney allograft has been described as a possible causal factor of lymphocele. OBJECTIVE: To analyze the possible relationship between lymphocele and acute cellular rejection. DESIGN: A retrospective study. SETTING: A referral hospital center. SAMPLE: 170 patients submitted to kidney transplantation from March 1992 to January 1997. A standard technique for renal transplantation was used. RESULTS: Of the 19 patients that developed lymphocele, 16 presented at least one episode of acute cell rejection (84%), and were treated with methylprednisolone. The relation between lymphocele and rejection was statistically significant (p = 0.04). Treatment of lymphocele consisted of peritoneal marsupialization in 3 patients (15.3%), percutaneous drainage in 7 (36.8%), laparascopic marsupialization in 2 (10.5%), and conservative treatment in 7 patients (36.8%). Evolution was favorable in 15 patients (78.9%), 1 patient (5.3%) died due to a cause unrelated to lymphocele, and 3 (15.8%) lost the graft due to immunological factors. The average follow-up period was 24.5 months. CONCLUSION: The high incidence of acute cell rejection in patients with lymphocele suggests a possible causal relationship between both conditions.
机译：背景：肾移植后淋巴膨大的发生率在0.6％至18％的病例之间变化，许多因素与其病因有关。肾同种异体移植的细胞排斥反应已被描述为淋巴膨出的可能原因。目的：分析淋巴囊肿与急性细胞排斥反应之间的可能关系。设计：一项回顾性研究。地点：转诊医院中心。样本：1992年3月至1997年1月，有170例患者接受了肾脏移植。采用了标准的肾脏移植技术。结果：在19例发展为淋巴膨出的患者中，有16例表现出至少一次急性细胞排斥反应（84％），并接受了甲泼尼龙治疗。淋巴囊肿与排斥反应之间的关系具有统计学意义（p = 0.04）。淋巴结肿大的治疗包括3例（15.3％）的腹膜有袋化，7例（36.8％）的经皮引流，2例（10.5％）的腹腔镜有囊化和7例（36.8％）的保守治疗。 15名患者（78.9％）的进化良好，1名患者（5.3％）因与淋巴膨出无关的原因死亡，3名（15.8％）由于免疫因素而失去了移植物。平均随访时间为24.5个月。结论：淋巴囊肿患者急性细胞排斥反应的发生率很高，提示这两种情况之间可能存在因果关系。

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