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首页> 外文期刊>Saudi journal of kidney diseases and transplantation : >Standard continuous ambulatory peritoneal dialysis therapy provides similar initial T-Kt/V regardless of the patient's peritoneal membrane transporter category: Single-center experience
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Standard continuous ambulatory peritoneal dialysis therapy provides similar initial T-Kt/V regardless of the patient's peritoneal membrane transporter category: Single-center experience

机译：无论患者的腹膜转运蛋白类别如何，标准的连续非卧床腹膜透析疗法均可提供相似的初始T-Kt / V：单中心经验

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Patients on continuous ambulatory peritoneal dialysis (CAPD) are routinely eva-luated using the peritoneal equilibrium test (PET) to determine the best method for achieving target total dialysis clearance (T-Kt/V). In this study, we tested the hypothesis that standard CAPD prescription would achieve an initial T-Kt/V of more than 1.7 in all the patients regardless of their PET measurements. This is a retrospective study that included patients who started standard CAPD of four two-liter exchanges per day. The study included 118 patients; their mean age was 51.5 years with a standard deviation (SD) of 14.39 years. There were 83 males (70.3%) and 35 females (29.7%). PET and Kt/V were performed during the first four to six weeks of the study. The PET classified the patients into four categories: 24 (20.3%), high transporters; 65 (55.1%), high average; 28 (23.7%), low average; and one (0.8%), low transporter. Patients were then divided in two groups: Group 1 comprised of the high transporters while Group 2 included all the other patients. The T-Kt/V of the two groups was similar; in Group 1, it was 2.57 (±1.17) and in Group 2 it was 2.50 (±0.88) (P = 0.77). The T-Kt/V of patients with no residual renal function was also similar; in Group 1 and Group 2 it was 1.8 (±0.29) and 1.97 (±0.56), respectively (P = 0.45). All patients in our study who started on standard CAPD treatment had an adequate initial T-Kt/V. Thus, our data demonstrate that all patients with end-stage renal disease can safely begin standard CAPD without PET, which only needs to be performed if the patient encounters trouble in his/her T-Kt/V or fluid removal.
机译：进行常规非卧床腹膜透析（CAPD）的患者常规进行腹膜平衡试验（PET）评估，以确定达到目标总透析清除率（T-Kt / V）的最佳方法。在这项研究中，我们检验了以下假设：无论患者采用何种PET测量，标准的CAPD处方均可使所有患者的初始T-Kt / V均超过1.7。这是一项回顾性研究，其中包括开始每天进行两次四升两次标准CAPD的患者。该研究包括118名患者。他们的平均年龄为51.5岁，标准差（SD）为14.39年。男83例（70.3％），女35例（29.7％）。在研究的前四到六周进行PET和Kt / V。 PET将患者分为四类：24（20.3％），高转运蛋白; 65（55.1％），平均水平高; 28（23.7％），平均水平低;一种（0.8％）低转运蛋白。然后将患者分为两组：第一组包括高转运蛋白，而第二组包括所有其他患者。两组的T-Kt / V相似。第1组为2.57（±1.17），第2组为2.50（±0.88）（P = 0.77）。没有残余肾功能的患者的T-Kt / V也相似。在第1组和第2组中，分别为1.8（±0.29）和1.97（±0.56）（P = 0.45）。我们研究中所有开始接受标准CAPD治疗的患者均具有足够的初始T-Kt / V。因此，我们的数据表明，所有患有晚期肾病的患者都可以安全地开始无PET的标准CAPD，只有在患者的T-Kt / V或排液困难时才需要执行。

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