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Which is the best schedule of autologous blood storage for preoperative adolescent idiopathic scoliosis patients?

机译：对于术前青春期特发性脊柱侧弯患者，自体血液存储的最佳时间表是什么？

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Background It is critically important for AIS patients to avoid perioperative allogeneic blood transfusions. Toward this aim, many institutes use autologous blood storage to perform perioperative transfusions. However, there is no standard timeline for collecting blood for storage. Therefore, the objective of this prospective cohort study was to compare the outcome of two different schedules for collecting autologous blood before operation in adolescent idiopathic scoliosis (AIS) patients. Methods Inclusion criteria are AIS patients, younger than 20 years old, female, operated between 2009 and 2013 with posterior spinal fusion and instrumentation who had 1600 mL autologous blood collected before operation. A total of 61 patients were participated in this study. They were randomly divided into 2 groups based on the storage interval. Weekly group (1W-G) consisted of 30 patients with a total of 1600mL blood collected weekly beginning 4 weeks before the operation. Biweekly group (2W-G) consisted of 31 patients with a total of 1600 mL blood collected biweekly beginning 8 weeks before the operation. The instrumented levels, total bleeding, complications during blood transfusion, and hematological examinations (RBC, Hb, Hct, MCH, MCV, MCHC) were evaluated. A hematological examination was performed before blood collection, before the operation, and on postoperative days 1, 3, and 7. Vasovagal reflex (VVR) was evaluated as complications during blood drawing. Result Mean age, height, and weight did not differ significantly between the 2 groups. There were no significant differences in instrumented levels, bleeding during operation, after operation, and collected blood during operation. With the autologous blood, allogeneic blood transfusion was completely avoided. VVR was more frequent in the biweekly group significantly (1W-G 4.2% vs 2W-G 15.3%). In terms of hematological examination, all values showed no significant differences between two groups in the pre-drawing and the pre-operation stage. However, the postoperative Hb and Hct values were higher in the weekly group. Also, MCV and MCHC showed the same behavior with higher values in the weekly group. Conclusion A weekly schedule of autologous blood storage is better than a biweekly storage schedule.
机译：背景技术对于AIS患者，避免围手术期异体输血至关重要。为了实现这一目标，许多机构使用自体血液存储进行围手术期输血。但是，没有收集血液的标准时间表。因此，该前瞻性队列研究的目的是比较两种在青少年特发性脊柱侧凸（AIS）患者手术前收集自体血的时间表的结果。方法纳入标准为2009年至2013年在AIS患者中，年龄小于20岁的女性，在2009年至2013年之间进行了脊柱后路融合和器械手术，并在手术前收集了1600 mL自体血。共有61名患者参加了这项研究。根据存储间隔将它们随机分为2组。每周组（1W-G）由30例患者组成，在手术前4周开始每周收集总计1600mL血液。每两周一次的小组（2W-G）由31例患者组成，在手术前8周开始每两周收集一次总计1600 mL血液。评估了仪器的水平，总出血量，输血期间的并发症和血液学检查（RBC，Hb，Hct，MCH，MCV，MCHC）。在采血之前，术前以及术后第1、3和7天进行了血液学检查。在抽血过程中，血管迷走神经反射（VVR）被评估为并发症。结果两组之间的平均年龄，身高和体重没有显着差异。仪器水平，手术中，手术后出血和手术中采血没有显着差异。使用自体血液，完全避免了异体输血。 VVR在两周一次组中更为频繁（1W-G 4.2％比2W-G 15.3％）。在血液学检查方面，在绘图前和手术前两组的所有值均无显着差异。但是，每周组的术后Hb和Hct值较高。此外，MCV和MCHC在每周组中表现出相同的行为，但值较高。结论每周一次的自体血液存储计划要优于每两周一次的血液存储计划。

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