Gene expression signature associated with BRAF mutations in human primary cutaneous melanomas

Caroline Kannengiesser; Alain Spatz; Stefan Michiels; Alain Eychène; Philippe Dessen; Vladimir Lazar; Véronique Winnepenninckx; Fabienne Lesueur; Sabine Druillennec; Caroline Robert; Joost J. van den Oord; Alain Sarasin; Brigitte Bressac-de Paillerets

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Gene expression signature associated with BRAF mutations in human primary cutaneous melanomas

机译：人类原发性皮肤黑色素瘤中BRAF突变相关的基因表达特征

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With the aim to correlate BRAF mutation status with gene expression in human primary cutaneous melanomas, and thus to get more insight on the consequences of BRAF mutation on cell biology, we analyzed all expression data obtained in melanomas from which D

机译：为了使BRAF突变状态与人类原发性皮肤黑色素瘤中的基因表达相关联，从而更深入地了解BRAF突变对细胞生物学的影响，我们分析了在所有黑色素瘤中获得的所有表达数据

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《Molecular oncology.》 |2008年第4期|共6页
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Caroline Kannengiesser; Alain Spatz; Stefan Michiels; Alain Eychène; Philippe Dessen; Vladimir Lazar; Véronique Winnepenninckx; Fabienne Lesueur; Sabine Druillennec; Caroline Robert; Joost J. van den Oord; Alain Sarasin; Brigitte Bressac-de Paillerets;
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中图分类肿瘤学;
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1. Real-world experience and clinical utility of a non-invasive gene expression test for primary cutaneous melanoma and validation against high risk driver mutations in BRAF, NRAS and the TERT promoter [J] . Ferris L., Moy R., Gerami P., The Journal of investigative dermatology. . 2018,第9期

机译：初次皮肤黑素瘤的无侵袭基因表达试验的现实世界经验和临床效用，以及BRAF，NRAS和TERT启动子的高危驾驶员突变验证
2. Clinical experience with a next-generation sequencing (NGS) test for BRAF and NRAS mutations along with gene expression profiling (GEP) in cutaneous melanoma (CM) [J] . Covington K. R., Kurley S. J., Meldi-Sholl L. E., The Journal of investigative dermatology. . 2019,第5Suppla1期

机译：对BRAF和NRAS突变的下一代测序（NGS）测试的临床经验以及皮肤黑素瘤（CM）中的基因表达分析（GEP）
3. BRAF mutations in cutaneous melanoma are independently associated with age, anatomic site of the primary tumor, and the degree of solar elastosis at the primary tumor site [J] . Bauer J., Büttner P., Murali R., Pigment cell & melanoma research . 2011,第2期

机译：皮肤黑色素瘤中的BRAF突变与年龄，原发肿瘤的解剖部位以及原发肿瘤部位的太阳弹性的程度独立相关
4. Gene Expression Models of BRAF Inhibitor Resistance in Melanoma Predict Drug Repurposing Candidates for Novel Combination Therapies [C] . Kelly Regan, Andrew R. Stiff, William E. Carson, International Molecular Medicine Tri-Conference. . 2016

机译：黑色素瘤中BRAF抑制剂抗性的基因表达模型预测了新型组合疗法的药物重新培养候选者
5. NRAS and BRAF mutations in primary cutaneous melanoma: A comparison of mutation rates between radial and vertical growth phases in individual tumors. [D] . Greene, Victoria R. 2007

机译：原发性皮肤黑素瘤中的NRAS和BRAF突变：单个肿瘤在径向和垂直生长期之间的突变率比较。
6. Gene expression signature associated with BRAF mutations in human primary cutaneous melanomas [O] . Caroline Kannengiesser, Alain Spatz, Stefan Michiels, 2008

机译：与人类原发性皮肤黑色素瘤的BRAF突变相关的基因表达特征
7. BRAF mutations in cutaneous melanoma are independently associated with age, anatomic site of the primary tumor, and the degree of solar elastosis at the primary tumor site [O] . Bauer, Jürgen, Büttner, Petra, Murali, Rajmohan, 2011

机译：皮肤黑色素瘤中的BRAF突变与年龄，原发肿瘤的解剖部位以及原发肿瘤部位的太阳弹性的程度独立相关

Gene expression signature associated with BRAF mutations in human primary cutaneous melanomas

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