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Fisiopatologia e aspectos inflamatórios da aterosclerose

机译:动脉粥样硬化的病理生理学和炎性方面

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Objective: To present and evaluate that have discovery recentely about physiopathology, epidemilogy and inflammatory aspects involved in atherosclerosis into multidisciplinary perpective. Source of dates: Bibliographical compilations were accomplished on original articles and revisions published in journals indexed in MEDLINE among 1970 to present that involved related subjects to atherosclerosis. Synthesis of dates: The revision of suggest that the atherosclerosis is a multifactorial disease with strong genetic component, environmental and inflammatory response ageing-related. However, its etyology still is not completely explained. Conclusion: The understanding of basic biology of the inflammation in atherosclerosis would provide a better clinical support that could alter the way of preventive medicine practice and provide benefice to public health.
机译:目的:介绍和评估最近发现的有关动脉粥样硬化的生理病理学,流行病学和炎性方面的发现,并将其纳入多学科研究。日期来源:书目汇编是根据1970年在MEDLINE收录的期刊上发表的原始文章和修订完成的,目的是介绍涉及动脉粥样硬化的相关主题。日期合成:的修订表明,动脉粥样硬化是一种多因素疾病,具有很强的遗传成分,与环境和炎症反应衰老相关。但是,其病因仍未完全解释。结论:对动脉粥样硬化炎症基本生物学的理解将提供更好的临床支持,从而可以改变预防医学实践的方式,并有益于公共卫生。

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