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首页> 外文期刊>Open Pharmaceutical Sciences Journal >Antimicrobial Studies and Characterization of Copper Surfactants Derived from Various Oils Treated at High Temperatures by P.D.A. Technique
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Antimicrobial Studies and Characterization of Copper Surfactants Derived from Various Oils Treated at High Temperatures by P.D.A. Technique

机译：由P.D.A.高温处理的各种油衍生的铜表面活性剂的抗菌研究和表征技术

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Introduction:Biologically potent compounds are one of the most important classes of materials for the upcoming generations. Increasing number of microbial infectious diseases and resistant pathogens create a demand and urgency to develop novel, potent, safe and improved variety of antimicrobial agents. This initiates a task for current chemistry to synthesize compounds that show promising activity as therapeutic agents with lower toxicity. Therefore, a substantial research is needed for their discovery and improvement. Chemistry of present era aims to build a pollution free environment. For the same, it targets to create some alternativeswhich are eco-friendly and nature loving. Present research work is a step towards achieving such alternatives.Method:For this the metallic soaps of copper (derived from common edible oils) were synthesized. The synthesized copper soaps have been confirmed by elemental analysis, UV, and IR spectroscopic technique. The fungicidal activities of copper soaps derived from soyabean, sesame oils have been evaluated by testing against Alternaria alternate and Aspergillus niger by P.D.A. technique. Result:The fungi toxicity results indicate that the strain of fungal species are susceptible towards these soaps and suggests that with the increase in concentration of copper soap it may increase further. The transition metallic soaps showed good antifungal activity because chelation increases the anti-microbial potency.
机译：简介：生物有效的化合物是后代最重要的材料类别之一。越来越多的微生物传染病和耐药病原体对开发新颖，有效，安全和改良的各种抗菌剂产生了需求和紧迫性。这启动了当前化学合成合成具有较低毒性的治疗剂的化合物的任务。因此，需要对它们的发现和改进进行大量研究。当前时代的化学旨在建立无污染的环境。同样，它的目标是创造一些生态友好和热爱大自然的选择。目前的研究工作是朝着实现这种替代方法迈出的一步。方法：为此，合成了铜的金属皂（源自普通食用油）。合成的铜皂已通过元素分析，紫外和红外光谱技术得到证实。大豆，芝麻油衍生的铜皂的杀真菌活性已通过P.D.A对交替链霉菌和黑曲霉的测试进行了评估。技术。结果：真菌毒性结果表明，真菌种类的菌株对这些肥皂敏感，并表明随着铜肥皂浓度的增加，它可能会进一步增加。过渡金属皂显示出良好的抗真菌活性，因为螯合增加了抗微生物效力。

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