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A Clinical Analysis to Detect Risk Factors of Chronic Subdural Hematoma Recurrence

机译:慢性硬膜下血肿复发危险因素临床分析

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Introduction: The etiology of recurrence of chronic subdural hematoma (CSDH) after surgical evacuation has not been completely understood until now, but several risk factors for recurrence have been reported. Meanwhile, the definitive risk factors have not been defined until now. Aim of Study: Analyze the potential risk factors, and emphasize preoperative, operative and post-operative ones for CSDH recurrence. Patients and Methods: This study is a prospective randomized clinical trial study including 82 patients with symptomatizing CSDH who underwent burr holes procedure and irrigation with closed system drainage for CSDH at Neurosurgical Department—Assuit University Hospital from July 2016 to July 2018. The possible factor studied for recurrence included age, hypertension, diabetes mellitus, liver diseases, Hemoglobin (Hb) level, prothrombin concentration and time (PC and PT), hematoma thickness and internal architecture, number of burr holes and position of drain, duration of drainage, amount of drainage and presence of postoperative residual hematoma on follow up CT brain. Multiple logistic regression analysis is used to assess the predictors of recurrence. Results: This study included 70 males and 12 females. The mean age was 58.9 years (range 34 - 93 years). 6 patients presented with recurrent CSDH. Age above 60 years, Hypertension, Diabetes mellitus (DM), prolong PT, separated and trabecular internal architecture of hematoma, and the thickness of hematoma more than 20 mm in pre-operative CT and postoperative residual hematoma were statistically significant factors for recurrence of CSDH. Conclusion: This information might be helpful in detecting patients with possible high incidence of recurrence and directing for close follow ups and acts that may reduce the incidence of recurrence.
机译:简介:到目前为止,外科排空术后慢性硬脑膜下血肿(CSDH)复发的病因尚不完全清楚,但已报道了一些复发的危险因素。同时,直到现在还没有确定的危险因素。研究目的:分析CSDH复发的潜在危险因素,并强调术前,术中和术后因素。患者与方法:这项研究是一项前瞻性随机临床试验研究,包括2016年7月至2018年7月在Assuit大学医院神经外科进行的82例有症状的CSDH的患者,这些患者接受了去毛刺手术并采用封闭系统引流冲洗CSDH。复发包括年龄,高血压,糖尿病,肝病,血红蛋白(Hb)水平,凝血酶原浓度和时间(PC和PT),血肿厚度和内部结构,毛刺孔数和引流位置,引流时间,引流量CT脑的引流和术后残留血肿的存在。多元逻辑回归分析用于评估复发的预测因子。结果:本研究包括70名男性和12名女性。平均年龄为58.9岁(范围34-93岁)。 6例患者表现为复发性CSDH。 60岁以上年龄,高血压,糖尿病,延长的PT,血肿的分离和小梁内部结构以及术前CT和术后残余血肿的血肿厚度超过20 mm是CSDH复发的统计学显着因素。结论:这些信息可能有助于发现可能复发的高发患者,并指导密切的随访和可能减少复发发生率的行为。

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