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Meeting Report: The Terabase Metagenomics Workshop and the Vision of an Earth Microbiome Project

机译:会议报告:Terabase元基因组学研讨会和地球微生物组项目的愿景

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Between July 18th and 24th 2010, 26 leading microbial ecology, computation, bioinformatics and statistics researchers came together in Snowbird, Utah (USA) to discuss the challenge of how to best characterize the microbial world using next-generation sequencing technologies. The meeting was entitled “Terabase Metagenomics” and was sponsored by the Institute for Computing in Science (ICiS) summer 2010 workshop program. The aim of the workshop was to explore the fundamental questions relating to microbial ecology that could be addressed using advances in sequencing potential. Technological advances in next-generation sequencing platforms such as the Illumina HiSeq 2000 can generate in excess of 250 billion base pairs of genetic information in 8 days. Thus, the generation of a trillion base pairs of genetic information is becoming a routine matter. The main outcome from this meeting was the birth of a concept and practical approach to exploring microbial life on earth, the Earth Microbiome Project (EMP). Here we briefly describe the highlights of this meeting and provide an overview of the EMP concept and how it can be applied to exploration of the microbiome of each ecosystem on this planet.
机译:在2010年7月18日至24日之间,有26位领先的微生物生态学,计算,生物信息学和统计学研究人员聚集在美国犹他州的斯诺伯德,讨论了如何利用下一代测序技术来最佳表征微生物世界的挑战。该会议名为“ Terabase元基因组学”,由科学计算研究所(ICiS)2010年夏季研讨会计划赞助。研讨会的目的是探讨与微生物生态学有关的基本问题,这些问题可以通过测序潜力的发展来解决。 Illumina HiSeq 2000等下一代测序平台的技术进步可以在8天之内生成超过2500亿碱基对的遗传信息。因此,产生一万亿个碱基对的遗传信息已成为日常工作。这次会议的主要成果是诞生了探索地球上微生物生命的概念和实践方法,即地球微生物组计划(EMP)。在这里,我们简要介绍了这次会议的重点,并概述了EMP概念以及如何将其用于探索地球上每个生态系统的微生物组。

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