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首页> 外文期刊>Substance Abuse Treatment, Prevention, and Policy >Sleep disturbance and its associations with severity of dependence, depression and quality of life among heroin-dependent patients: a cross-sectional descriptive study
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Sleep disturbance and its associations with severity of dependence, depression and quality of life among heroin-dependent patients: a cross-sectional descriptive study

机译:依赖海洛因的患者的睡眠障碍及其与依赖性的严重程度,抑郁和生活质量的关系:一项横断面描述性研究

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Background Sleep disturbance is common and may adversely affect treatment outcome, mental health, and quality of life in heroin-dependent patients. Previous studies have focused upon patients receiving treatment. We conducted a cross-sectional descriptive study to explore the 1-month prevalence of sleep disturbance and its associations with socio-demographic, substance-related characteristics, severity of dependence, severity of depression, and quality of life among heroin-dependent patients before entering treatment program. Methods The sample ( n =?514) comprised individuals with heroin dependence attending the methadone maintenance treatment program and the therapeutic community at a psychiatric center in Nantou, Taiwan between 2008 and 2014. Sleep quality was measured using Pittsburgh Sleep Quality Index (PSQI) with a global score greater than 5 indicating sleep disturbance. Centre for Epidemiologic Studies Depression Scale, Severity of Dependence Scale, and World Health Organization Quality of Life-BREF were also approached. T-test, chi-square tests, and multivariate logistic regression were performed to measure associations between variables and sleep disturbance. Results The 1-month prevalence of sleep disturbance (PSQI?>?5) was 76.3% among 514 subjects with heroin dependence. Heroin users with sleep disturbance had significantly more life events in the previous year, higher rate of unemployment, greater cigarette consumption, more substance related criminal convictions, longer length of heroin use, higher rate of injectors, greater severity of dependence, greater severity of depression, and lower quality of life compared to those without sleep disturbance. Severity of dependence, severity of depression, and physical health domain of quality of life remained significantly associated with sleep disturbance after adjusting for other variables. Conclusion Heroin-dependent patients had a high 1-month prevalence of sleep disturbance, and this was associated with greater severity of dependence, greater severity of depression, and poorer physical health-related quality of life. Early assessments and interventions for sleep disturbance among patients with heroin dependence are recommended.
机译:背景睡眠障碍很常见,并且可能对依赖海洛因的患者的治疗结果,心理健康和生活质量产生不利影响。先前的研究集中于接受治疗的患者。我们进行了一项横断面描述性研究,以探讨进入海洛因依赖患者入院前1个月的睡眠障碍患病率及其与社会人口统计学,药物相关特征,依赖性的严重程度,抑郁的严重程度以及生活质量的相关性治疗方案。方法2008年至2014年之间,样本(n =?514)包括参加美沙酮维持治疗计划和台湾南投精神病学中心治疗社区的海洛因依赖者。使用匹兹堡睡眠质量指数(PSQI)对睡眠质量进行测量。总分大于5表示睡眠障碍。流行病学研究中心的抑郁量表,依赖性严重程度量表和世界卫生组织的生活质量-BREF也进行了研究。进行了T检验,卡方检验和多元Logistic回归,以测量变量与睡眠障碍之间的关联。结果在514名海洛因依赖者中,睡眠障碍的1个月患病率(PSQI≥5)为76.3%。患有睡眠障碍的海洛因使用者在去年的生活事件显着增多,失业率更高,卷烟消费量更多,与毒品有关的刑事定罪次数更多,海洛因使用时间更长,注射剂的使用率更高,依赖性的严重程度更高,抑郁的严重程度更高和没有睡眠障碍的人相比生活质量较低。调整其他变量后,依赖性的严重程度,抑郁的严重程度以及身体质量的健康状况仍然与睡眠障碍显着相关。结论海洛因依赖患者的睡眠障碍患病率高1个月,这与依赖严重程度,抑郁严重程度以及与身体健康相关的生活质量较差有关。建议早期评估和干预海洛因依赖患者的睡眠障碍。

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