Background. Infant colic is a common benign disease during early infancy. Migraine and tension-type headache (TTH) are the most common primary headache forms among pediatric population. Several studies have investigated the incidence of infant colic in patients with migraine and TTH. The meta-analysis was to assess the relationship between infant colic and migraine as well as TTH. Methods. PubMed, Web of Science, and Cochrane Library were searched until August 16, 2018, for potential studies. Data were extracted by two independent authors and analyzed using RevMan 5.2 software. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated to determine the association between infant colic and migraine as well as TTH, respectively. Results. A total of 148 studies were found, and 7 studies were finally included. A higher incidence of colic during infancy was revealed in migraine patients than controls (, OR: 2.51, 95% CI: 1.32–4.77) and TTH subjects (, OR: 0.33, 95% CI: 0.13–0.86), respectively. And no significances were found between TTHs with controls (, OR: 1.17, 95% CI: 0.73–1.89). Conclusion. This meta-analysis indicated that migraine was associated with increased incidence of infantile colic history, but TTH incidence was not relevant with the incidence of infantile colic history.
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机译：背景。婴儿绞痛是婴儿早期的常见良性疾病。偏头痛和紧张型头痛（TTH）是儿童人群中最常见的原发性头痛形式。几项研究调查了偏头痛和TTH患者婴儿绞痛的发生率。荟萃分析旨在评估婴儿绞痛与偏头痛以及TTH之间的关系。方法。搜索PubMed，Web of Science和Cochrane图书馆直至2018年8月16日，以进行潜在研究。数据由两名独立作者提取，并使用RevMan 5.2软件进行分析。计算具有95％置信区间（CI）的几率（OR），分别确定婴儿绞痛和偏头痛以及TTH之间的关联。结果。共找到148个研究，最后纳入7个研究。偏头痛患者婴儿期绞痛的发生率分别高于对照组（OR：2.51、95％CI：1.32-4.77）和TTH受试者（OR：0.33、95％CI：0.13-0.86）。在与对照的TTH之间未发现显着性（或：1.17，95％CI：0.73-1.89）。结论。这项荟萃分析表明，偏头痛与婴儿绞痛史的发生率增加有关，但TTH发病率与婴儿绞痛史的发生率无关。
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