Assessing the Subjective and Physiological Effects of Intranasally Administered Crushed Extended-Release Morphine Formulations with and without a Sequestered Naltrexone Core in Recreational Opioid Users

Beatrice Setnik Veeraindar Goli Naama Levy-Cooperman Catherine Mills Megan Shram; Ira Smith

首页> 外文期刊>Pain research & management: the journal of the Canadian Pain Society = journal de la socie?te? canadienne pour le traitement de la douleur >Assessing the Subjective and Physiological Effects of Intranasally Administered Crushed Extended-Release Morphine Formulations with and without a Sequestered Naltrexone Core in Recreational Opioid Users

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Assessing the Subjective and Physiological Effects of Intranasally Administered Crushed Extended-Release Morphine Formulations with and without a Sequestered Naltrexone Core in Recreational Opioid Users

机译：在娱乐性阿片类药物使用者中评估有和没有隔离纳曲酮核心的鼻内给药粉碎延缓释放吗啡制剂的主观和生理效应

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OBJECTIVE: To evaluate the pharmacodynamic (PD) effects of morphine sulfate and naltrexone hydrochloride extended-release (MSN) capsules compared with controlled-release morphine sulfate (MS) and placebo when crushed and administered intranasally.

机译：目的：与经控释的硫酸吗啡（MS）和安慰剂相比，经鼻内压碎和给药后，比较硫酸吗啡和盐酸纳曲酮缓释（MSN）胶囊的药效学（PD）效果。

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《Pain research & management: the journal of the Canadian Pain Society = journal de la socie?te? canadienne pour le traitement de la douleur》 |2013年第1期|共页
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Beatrice Setnik Veeraindar Goli Naama Levy-Cooperman Catherine Mills Megan Shram; Ira Smith;
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中图分类麻醉学;
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1. Assessing the subjective and physiological effects of intranasally administered crushed extended-release morphine formulations with and without a sequestered naltrexone core in recreational opioid users [J] . Setnik Beatrice, Goli Veeraindar, Levy-Cooperman Naama, Pain research & management: the journal of the Canadian Pain Society = journal de la socie?te? canadienne pour le traitement de la douleur . 2013,第4期

机译：在娱乐性阿片类药物使用者中评估含和不含纳曲酮核心的鼻内镇静缓释吗啡制剂的镇痛作用
2. Intranasal Administration of Crushed ALO-02 (Extended-Release Oxycodone With Sequestered Naltrexone): A Randomized, Controlled Abuse-Potential Study in Nondependent Recreational Opioid Users [J] . The Journal of Clinical Pharmacology: Official Journal of the American College of Clinical Pharmacology . 2015,第12期

机译：粉碎的ALO-02（隔离型纳曲酮的扩展释放羟考酮）的鼻内给药：非依赖性休闲类鸦片使用者的随机，受控滥用潜能研究
3. Assessment of pharmacodynamic effects following oral administration of crushed morphine sulfate and naltrexone hydrochloride extended-release capsules compared with crushed morphine sulfate controlled-release tablets and placebo in nondependent recreational opioid users [J] . SetnikB., SommervilleK., GoliV., Pain medicine : . 2013,第8期

机译：非依赖性休闲阿片类药物使用者对硫酸吗啡和盐酸纳曲酮缓释胶囊与硫酸吗啡控释片剂和安慰剂相比口服给药后的药效学评估
4. Assessing the subjective and physiological effects of intranasally administered crushed extended-release morphine formulations with and without a sequestered naltrexone core in recreational opioid users [O] . Beatrice Setnik, Veeraindar Goli, Naama Levy-Cooperman, 2013

机译：在娱乐性阿片类药物使用者中评估含和不含纳曲酮核心的鼻内镇静缓释吗啡制剂的镇痛作用
5. Human Abuse Potential of an Abuse-Deterrent (AD), Extended-Release (ER) Morphine Product Candidate (Morphine-ADER Injection-Molded Tablets) vs Extended-Release Morphine Administered Intranasally in Nondependent Recreational Opioid Users [O] . Lynn R. Webster, Michael D. Smith, John Lawler, 2016

机译：滥用滥用（AD），延长释放（ER）吗啡产品候选（吗啡 - 涂剂注塑片剂）与鼻内诊断娱乐阿片类药物鼻内施用的延长释放吗啡（ER）吗啡潜在

Assessing the Subjective and Physiological Effects of Intranasally Administered Crushed Extended-Release Morphine Formulations with and without a Sequestered Naltrexone Core in Recreational Opioid Users

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