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首页> 外文期刊>Pain research & management: the journal of the Canadian Pain Society = journal de la socie?te? canadienne pour le traitement de la douleur >Depressed Mood Differentially Mediates the Relationship between Pain Intensity and Pain Disability Depending on Pain Duration: A Moderated Mediation Analysis in Chronic Pain Patients
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Depressed Mood Differentially Mediates the Relationship between Pain Intensity and Pain Disability Depending on Pain Duration: A Moderated Mediation Analysis in Chronic Pain Patients

机译：抑郁的情绪差异取决于疼痛持续时间的疼痛强度和疼痛残疾之间的关系：慢性疼痛患者的调解分析。

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Research has shown that pain is associated with disability and that depressed mood mediates the relationship between pain and disability. The question of whether duration of pain moderates these effects was addressed in this cross-sectional study with 356 chronic pain patients. A simple mediation model replicated the notion that depressed mood explains a significant proportion of the relationship between pain and disability (in the study at hand: 12%). A moderated mediation model revealed that the indirect effect of pain on disability through depressed mood is moderated by pain duration: while depressed mood did not mediate the effect of pain on disability in chronic pain patients with shorter pain duration, depressed mood significantly mediated the effect pain exerts on disability in chronic pain patients with longer pain duration. Pain duration did not moderate the direct effect of pain on disability. Implications of these findings for the treatment of chronic pain might be that targeting depressed mood is especially relevant in chronic pain patients with longer pain duration to reduce the effect of pain on disability.
机译：研究表明，疼痛与残疾有关，沮丧的情绪介导了疼痛与残疾之间的关系。在这项针对356名慢性疼痛患者的横断面研究中，解决了疼痛持续时间是否减轻这些影响的问题。一个简单的调解模型复制了以下观点：情绪低落可以解释疼痛和残疾之间的很大比例关系（在本研究中：12％）。一个适度的调解模型显示，疼痛持续时间可减轻疼痛通过情绪低落对残疾的间接影响：虽然抑郁情绪并未介导疼痛持续时间较短的慢性疼痛患者对疼痛对残疾的影响，但情绪低落明显介导了疼痛的影响在持续较长疼痛的慢性疼痛患者中发挥残疾作用。疼痛持续时间并未减轻疼痛对残疾的直接影响。这些发现对治疗慢性疼痛的暗示可能是，针对抑郁情绪的治疗在疼痛持续时间较长的慢性疼痛患者中尤其重要，以减少疼痛对残疾的影响。

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