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Sleep Quality and Quality of Life in COPD Patients with and without Suspected Obstructive Sleep Apnea

机译：患有和不患有阻塞性睡眠呼吸暂停的COPD患者的睡眠质量和生活质量

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Present study was designed to obtain association between sleep apnea with sleep quality and quality of life in COPD patients. This cross-sectional descriptive study was conducted on 139 patients with COPD in a chest clinic of a university hospital. All patients were evaluated by pulmonary function test for determination of severity of their disease. Also, Berlin questionnaire, Epworth sleepiness scale, Pittsburgh Sleep Quality Index, and St. George Respiratory questionnaires (SGRQ) were employed for assessment of patients. Analysis of data showed that quality of sleep was significantly correlated with quality of life (P<0.001). About half of the patients were at high risk for sleep apnea. The patients were divided into two groups according to the result of Berlin questionnaire. Significant differences were found between the groups for total score and each of three subscores of SGRQ suggesting worse quality of life in overlap syndrome (P<0.001). Also, patients with overlap syndrome had worse quality of sleep compared to patients without it (8.1±1.7versus6.2±2.3;P<0.001). Stepwise multiple regression analysis showed that severity of COPD, coexisting obstructive sleep apnea, and sleep quality accounted for the SGRQ significantly (r2(coefficient of determination) = 0.08, 0.21, and 0.18, resp.). It is recommended that patient with COPD be evaluated for sleep apnea and sleep disorders during routine examinations and followups.
机译：本研究旨在获得COPD患者睡眠呼吸暂停与睡眠质量和生活质量之间的关联。这项横断面描述性研究是在大学医院的胸部诊所对139例COPD患者进行的。通过肺功能测试评估所有患者的疾病严重程度。此外，还使用了柏林问卷，爱泼华嗜睡量表，匹兹堡睡眠质量指数和圣乔治呼吸问卷（SGRQ）来评估患者。数据分析表明，睡眠质量与生活质量显着相关（P <0.001）。大约一半的患者有睡眠呼吸暂停的高风险。根据柏林问卷调查的结果将患者分为两组。在总分和SGRQ的三个子评分中，各组之间存在显着差异，表明重叠综合征的生活质量较差（P <0.001）。此外，重叠综合征患者的睡眠质量比没有重叠综合征的患者差（8.1±1.7对6.2±2.3; P <0.001）。逐步多元回归分析表明，COPD的严重程度，阻塞性睡眠呼吸暂停并存和睡眠质量均占SGRQ的比重（r2（测定系数）分别为0.08、0.21和0.18）。建议在常规检查和随访期间对COPD患者进行睡眠呼吸暂停和睡眠障碍评估。

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