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Physiological Sleep Propensity Might Be Unaffected by Significant Variations in Self-Reported Well-Being, Activity, and Mood

机译:自我报告的幸福感,活动和情绪上的显着变化可能不会影响生理睡眠倾向

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Background and Objective. Depressive state is often associated with such physical symptoms as general weakness, fatigue, tiredness, slowness, reduced activity, low energy, and sleepiness. The involvement of the sleep-wake regulating mechanisms has been proposed as one of the plausible explanations of this association. Both physical depressive symptoms and increased physiological sleep propensity can result from disordered and insufficient sleep. In order to avoid the influence of disordered and insufficient sleep, daytime and nighttime sleepiness were tested in winter depression characterized by normal night sleep duration and architecture.Materials and Methods. A total sample consisted of 6 healthy controls and 9 patients suffered from depression in the previous winter season. Sleep latency was determined across 5 daytime and 4 nighttime 20-min attempts to nap in summer as well as in winter before and after a week of 2-hour evening treatment with bright light.Results and Conclusions. Patients self-reported abnormally lowered well-being, activity, and mood only in winter before the treatment. Physiological sleep propensity was neither abnormal nor linked to significant changes in well-being, activity, and mood following the treatment and change in season. It seems unlikely that the mechanisms regulating the sleep-wake cycle contributed to the development of the physical depressive symptoms.
机译:背景和目标。抑郁状态通常与身体症状有关,例如全身无力,疲倦,疲倦,缓慢,活动减少,精力不足和嗜睡。已经提出了睡眠-唤醒调节机制的参与作为该关联的合理解释之一。身体紊乱和睡眠不足均可导致身体抑郁症状和生理睡眠倾向增加。为了避免混乱和睡眠不足的影响,在以正常夜间睡眠时间和结构为特征的冬季抑郁症中测试了白天和夜间的嗜睡性。材料和方法。总样本包括6个健康对照和9个在上一个冬季患抑郁症的患者。在夏季以及冬季进行2小时夜间强光照射一周之前和之后的5个白天和4个夜间20分钟的小睡时间中确定睡眠潜伏期。结果和结论。自我报告的患者仅在治疗前的冬季异常降低了健康,活动和情绪。治疗后和季节变化后,生理睡眠倾向既不异常也不与健康,活动和情绪的显着变化相关。调节睡眠-觉醒周期的机制似乎不太可能导致身体抑郁症状的发展。

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