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首页> 外文期刊>Pain research & management: the journal of the Canadian Pain Society = journal de la socie?te? canadienne pour le traitement de la douleur >Effectiveness of Sequential Viscosupplementation in Temporomandibular Joint Internal Derangements and Symptomatology: A Case Series
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Effectiveness of Sequential Viscosupplementation in Temporomandibular Joint Internal Derangements and Symptomatology: A Case Series

机译：在颞下颌关节内部排列紊乱和症状学中顺序补充黏液的有效性：一个病例系列

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摘要

Viscosupplementation is a minimally invasive technique that replaces synovial fluid by intra-articular injection of hyaluronic acid (HA). Although effective in some joints, there is not conclusive evidence regarding temporomandibular disorders. This case series described the efficacy of a viscosupplementation protocol in intra-articular temporomandibular disorders. Ten patients with a diagnosis of disc displacement and/or osteoarthritis by Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) were submitted to four monthly injections of low or medium molecular weight HA. Pain, mandibular function, image analysis by tomography and magnetic resonance, and quality of life were assessed at baseline and follow-ups (1 and 6 months). Pain, jaw range-of-motion, mandibular function, and quality of life improved at follow-up evaluations. Osteoarthritis changes decreased, and 20% of patients improved mandibular head excursion after treatment. Resolution of effusion and improvement in disc morphology were observed for most patients. This viscosupplementation protocol reduced pain and symptoms associated with internal derangement of temporomandibular joint, improved quality of life, and showed benefits from both low and medium molecular weight HA in alternate cycles.
机译：粘液补充是一种微创技术，通过关节内注射透明质酸（HA）代替滑液。尽管在某些关节中有效，但尚无确凿的证据证明颞下颌关节疾病。该病例系列描述了黏膜补充方案在关节内颞下颌关节疾病中的功效。十名根据《颞下颌疾病研究诊断标准》（RDC / TMD）诊断为椎间盘移位和/或骨关节炎的患者接受了每月四次低分子量或中等分子量HA的注射。在基线和随访（1个月和6个月）中评估疼痛，​​下颌功能，层析成像和磁共振图像分析以及生活质量。在随访评估中，疼痛，下颌活动范围，下颌功能和生活质量得到改善。骨关节炎变化减少，治疗后20％的患者改善了下颌头的偏移。大多数患者观察到积液的消退和椎间盘形态的改善。该粘膜补充方案减少了与颞下颌关节内部紊乱相关的疼痛和症状，改善了生活质量，并显示了在交替周期中低分子量和中等分子量HA的益处。

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