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首页> 外文期刊>Pain Research and Treatment >Physical, Cognitive, and Psychosocial Predictors of Functional Disability and Health-Related Quality of Life in Adolescents with Neurofibromatosis-1
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Physical, Cognitive, and Psychosocial Predictors of Functional Disability and Health-Related Quality of Life in Adolescents with Neurofibromatosis-1

机译：患有神经纤维瘤病1的青少年的功能障碍和健康相关生活质量的身体，认知和社会心理预测因素

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Objective. To examine physical, cognitive, and social-emotional predictors of quality of life (HRQOL) and functional disability (FD) in adolescents diagnosed with Neurofibromatosis-1.Methods. Participants were twenty-seven adolescents with a diagnosis of NF-1 who were recruited through an NF-1 specialty clinic at a large Midwestern children’s hospital. Measurements of the adolescents’ cognitive functioning, pain, FD, HRQOL, and social and emotional functioning were obtained with corresponding parent measures.Results. Emotional functioning significantly predicted youth-reported and parent-reported HRQOL, whereas days of pain significantly predicted youth-reported FD.Conclusions. NF-1 is a complex disease. Measurements of the overall impact of the disease tap into different aspects of the effects of NF-1 on daily life. Global outcomes such as HRQOL appear to be influenced especially by emotional functioning, whereas outcomes such as FD appear to be influenced by the physical/organic aspects of NF-1.
机译：目的。目的检查在诊断为神经纤维瘤病-1的青少年中生活质量（HRQOL）和功能障碍（FD）的身体，认知和社会情感预测因子。参加调查的是27位诊断为NF-1的青少年，这些青少年是通过中西部一家大型儿童医院的NF-1专科诊所招募的。通过相应的家长测评获得了青少年的认知功能，疼痛，FD，HRQOL以及社交和情绪功能的测量结果。情绪功能显着预测青年报告的和父母报告的HRQOL，而痛苦的日子显着预测青年报告的FD。 NF-1是一种复杂的疾病。对疾病总体影响的测量涉及NF-1对日常生活影响的不同方面。诸如HRQOL之类的总体结果似乎尤其受情绪功能的影响，而诸如FD之类的结果似乎受NF-1的物理/有机方面的影响。

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