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Depressive Symptoms, Pain, and Quality of Life among Patients with Nonalcohol-Related Chronic Pancreatitis

机译：非酒精相关性慢性胰腺炎患者的抑郁症状，疼痛和生活质量

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Objective. The present study was conducted to determine if depressive symptoms were associated with variability in pain perception and quality of life among patients with nonalcohol-related chronic pancreatitis.Methods.The research design was cross-sectional, and self-report data was collected from 692 patients with nonalcohol-related, intractable pancreatitis. The mean age of the sample was 52.6 (SD=14.7); 41% of the sample were male. Participants completed the MOS SF12 Quality of Life Measure, the Center for Epidemiological Studies 10-item Depression Scale (CESD), and a numeric rating scale measure of “pain on average” from the Brief Pain Inventory.Results.Depressive symptoms were significantly related to participants’ reports of increased pain and decreased quality of life. The mean CESD score of the sample was 10.6 (SD=6.5) and 52% of the sample scored above the clinical cutoff for the presence of significant depressive symptomology. Patients scoring above the clinical cutoff on the depression screening measure rated their pain as significantly higher than those below the cutoff (P<0.0001) and had significantly lower physical quality of life (P<0.0001) and lower mental quality of life (P<0.0001).Conclusion.Although causality cannot be determined based on cross-sectional, correlational data, findings suggest that among patients with nonalcoholic pancreatitis, the presence of depressive symptoms is common and may be a risk factor associated with increased pain and decreased quality of life. Thus, routine screening for depressive symptomology among patients with nonalcoholic pancreatitis may be warranted.
机译：目的。本研究旨在确定非酒精相关性慢性胰腺炎患者的抑郁症状是否与疼痛感知和生活质量的变异性有关。方法。研究设计是横断面的，并收集了692例患者的自我报告数据与非酒精相关的顽固性胰腺炎。样本的平均年龄为52.6（SD = 14.7）;样本中有41％是男性。参与者完成了MOS SF12生活质量量度，流行病学研究中心10项抑郁量表（CESD）以及简短疼痛量表中“平均疼痛”的数字量表量度。结果。抑郁症状与参与者关于疼痛增加和生活质量下降的报告。样本的平均CESD评分为10.6（SD = 6.5），并且有52％的样本因存在明显的抑郁症状而得分高于临床临界值。在抑郁筛查指标上得分高于临床临界值的患者将其疼痛评估为明显高于临界值以下的患者（P <0.0001），身体生活质量（P <0.0001）明显较低，心理生活质量（P <0.0001）较低结论：尽管不能根据横断面的相关数据确定因果关系，但研究结果表明在非酒精性胰腺炎患者中，抑郁症状很常见，并且可能是与疼痛加剧和生活质量下降相关的危险因素。因此，可能需要常规筛查非酒精性胰腺炎患者的抑郁症状。

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