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The Associations between Pain Sensitivity and Knee Muscle Strength in Healthy Volunteers: A Cross-Sectional Study

机译:健康志愿者的疼痛敏感性与膝部肌肉力量之间的关联:跨部门研究

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Objectives. To investigate associations between muscle strength and pain sensitivity among healthy volunteers and associations between different pain sensitivity measures.Methods. Twenty-eight healthy volunteers (21 females) participated. Pressure pain thresholds (PPTs) were obtained from 1) computer-controlled pressure algometry on the vastus lateralis and deltoid muscles and on the infrapatellar fat pad and 2) computerized cuff pressure algometry applied on the lower leg. Deep-tissue pain sensitivity (intensity and duration) was assessed by hypertonic saline injections into the vastus lateralis, deltoid, and infrapatellar fat pad. Quadriceps and hamstring muscle strength was assessed isometrically at 60-degree knee flexion using a dynamometer. Associations between pain sensitivity and muscle strength were investigated using multiple regressions including age, gender, and body mass index as covariates.Results. Knee extension strength was associated with computer-controlled PPT on the vastus lateralis muscle. Computer-controlled PPTs were significantly correlated between sites (r>0.72) and with cuff PPT (r>0.4). Saline induced pain intensity and duration were correlated between sites (r>0.39) and with all PPTs (r<-0.41).Conclusions. Pressure pain thresholds at the vastus lateralis are positively associated with knee extensor muscle strength. Different pain sensitivity assessment methods are generally correlated. The cuff PPT and evoked infrapatellar pain seem to reflect the general pain sensitivity. This trial is registered with ClinicalTrials.gov:NCT01351558.
机译:目标。研究健康志愿者的肌肉力量与疼痛敏感性之间的关联以及不同疼痛敏感性措施之间的关联。 28名健康志愿者(21名女性)参加了比赛。压力疼痛阈值(PPT)可以通过以下方式获得:1)计算机控制的外侧臀肌和三角肌以及pat下脂肪垫上的压力法,以及2)应用于小腿的袖套压力法。通过向股外侧肌,三角肌和pat下脂肪垫中注射高渗盐水来评估深部组织疼痛敏感性(强度和持续时间)。使用测力计在60度屈膝时等距评估股四头肌和绳肌的力量。使用年龄,性别和体重指数作为协变量的多元回归研究疼痛敏感性和肌肉力量之间的关系。膝关节伸展力量与外侧股肌的计算机控制PPT相关。计算机控制的PPT与部位之间(r> 0.72)和袖套PPT(r> 0.4)显着相关。盐水诱导的疼痛强度和持续时间与部位之间(r> 0.39)以及所有PPTs(r <-0.41)相关。股外侧肌的压力疼痛阈值与膝伸肌力量呈正相关。不同的疼痛敏感性评估方法通常相关。袖带PPT和诱发的in下疼痛似乎反映了一般的疼痛敏感性。该试验已在ClinicalTrials.gov:NCT01351558上注册。

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