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首页> 外文期刊>Pain Studies and Treatment >Case report: Effect of immunoglobulin on pain in Post-Polio Syndrome—Three case reports
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Case report: Effect of immunoglobulin on pain in Post-Polio Syndrome—Three case reports

机译：病例报告：免疫球蛋白对脊髓灰质炎后综合症疼痛的影响-三例病例报告

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摘要

Study design: Case reports. Setting: University hospital setting. Objective: To analyze the effect of intravenous immunoglobulin on neuropathic and nociceptive pain in three patients with Post-Polio Syndrome (PPS). Materials and Methods: Three patients with PPS and pain who received treatment with 90 g IvIg are described. Results: Before treatment one of the patients had pure neuropathic pain and the other two had a combination of neuropathic and nociceptive pain. There was no effect on pain in the patient with pure neuropathic pain and only effect on the nociceptive pain in the patients with a combination of neuropathic and nociceptive pain. Discussion: Pain is one of the most common symptoms in PPS. Previous studies have shown an effect on pain in PPS patients receiving IvIg. The results of the present study point to that the effect on pain is limited to nociceptive pain and that there is no effect on neuropathic pain which leads to increased knowledge of characterization of responders of IvIg treatment. Conclusion: IvIg treatment treatmentreduces nociceptive but not neuropathic pain in PPS patients.
机译：研究设计：病例报告。单位：大学医院。目的：分析静脉注射免疫球蛋白对三名脊髓灰质炎后综合征（PPS）患者的神经性和伤害性疼痛的影响。材料和方法：描述了接受90 g IvIg治疗的3例PPS和疼痛患者。结果：在治疗之前，其中一名患者患有纯净的神经性疼痛，而另两名患者则患有神经性和伤害性疼痛的组合。纯神经性疼痛患者对疼痛没有影响，而神经性疼痛和伤害性疼痛相结合的患者仅对伤害性疼痛有影响。讨论：疼痛是PPS中最常见的症状之一。先前的研究表明，接受IvIg的PPS患者可缓解疼痛。本研究的结果指出，对疼痛的作用仅限于伤害性疼痛，对神经性疼痛没有作用，这导致对IvIg治疗反应者的特征了解增加。结论：IvIg治疗可减轻PPS患者的伤害性疼痛，但不能减轻神经性疼痛。

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