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首页> 外文期刊>Pakistan journal of medical sciences. >Implantation metastasis of rectosigmoid cancer in an anal fistula
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Implantation metastasis of rectosigmoid cancer in an anal fistula

机译：直肠乙状结肠癌在肛瘘中的植入转移

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Implantation metastasis of colorectal cancer in an anal fistula is very rare. We report a case of a 61 years old male who underwent fistulectomy for an anal fistula. Histopathology unexpectedly revealed adenocarcinoma in the fistula track, however the patient refused further treatment. Sixteen months later he presented with an obstructing locally advanced rectosigmoid cancer found to be fixed into the pelvic wall. An ileosigmoid bypass was fashioned and he was treated with neoadjuvant chemoradiotherapy followed by high anterior resection. Histopathology confirmed a colorectal adenocarcinoma, Immunohistochemistry of the tumors from both sites was CK7-/CK20+. The patient died 34 months later with liver and lung metastasis however no perianal recurrence occurred. Local resection with or without radiotherapy, instead of abdominoperineal resection, was feasible for control of perianal metastatic lesion implanted from colorectal cancer if local extended resection was possible.
机译：大肠癌在肛瘘中的植入转移非常罕见。我们报告了一例61岁男性因肛瘘行瘘管切除术的病例。组织病理学意外地在瘘管径迹中发现了腺癌，但是患者拒绝进一步治疗。 16个月后，他出现了一种阻塞在局部骨盆壁的局部晚期直肠乙状结肠癌。形成了乙状结肠乙状结肠旁路术，他接受了新辅助放化疗治疗，然后进行高位前切除术。组织病理学证实为大肠腺癌，两个部位的肿瘤的免疫组织化学均为CK7- / CK20 +。该患者在34个月后因肝和肺转移而死亡，但未发生肛周复发。如果可能进行局部扩大切除术，则可以采用有或没有放疗的局部切除术代替腹部手术切除术来控制结直肠癌植入的肛周转移病变。

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