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首页> 外文期刊>Patient Preference and Adherence >Prevalence Of Potentially Inappropriate Medication In The Older Adult Population Within Primary Care In Portugal: A Nationwide Cross-Sectional Study
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Prevalence Of Potentially Inappropriate Medication In The Older Adult Population Within Primary Care In Portugal: A Nationwide Cross-Sectional Study

机译：葡萄牙初级保健范围内老年人口潜在不当用药的普遍性：全国性跨部门研究

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Background: In potentially inappropriate medications harm potentially outweighs benefits. Even appropriately prescribed medications may become inappropriate. They can lead to a high risk of adverse drug reactions, morbidity and mortality. The aim of this study was to determine the prevalence of potentially inappropriate medication in the older adult population attending primary care in Portugal and to identify associated sociodemographic and clinical factors. Methods: We conducted a cross-sectional, analytical study in primary care centres from the five Portuguese healthcare administrative regions and the two autonomous regions. We used a random sample of 757 older patients provided by the information department of the ministry of health (SPMS) and family doctors from the autonomous regions. Data collection occurred March 2018 and we studied sociodemographic characteristics, clinical profile and medication. We used 2015 Beers Criteria to assess potentially inappropriate medications. Logistic regression analyses were performed to determine associations between potentially inappropriate medications’ prescriptions and other variables. Results: Potentially inappropriate medication was present in 68.6% and 46.1% of the sample had two or more. The likelihood of having potentially inappropriate medication increased significantly with being female (OR=1.56 [1.05 to 2.31]), number of chronic health problems (OR=1.06 [1.01 to 1.13]), number of pharmacological subclasses (OR=1.40 [1.30 to 1.51]) and number of prescribers (OR=1.34 [1.09 to 1.65]). Proton-pump inhibitors, nonsteroidal anti-inflammatory drugs and benzodiazepines were the most commonly found ones. Conclusion: Potentially inappropriate medication in older adults was found to be a common occurrence in Portugal. It is important that doctors are aware of this problem, namely in the primary care setting due to the longitudinal care.
机译：背景：在潜在不适当的药物中，危害可能大于收益。甚至适当开处方的药物也可能变得不合适。它们可能导致药物不良反应，发病率和死亡率的高风险。这项研究的目的是确定在葡萄牙接受初级保健的老年人口中潜在不适当药物的流行率，并确定相关的社会人口统计学和临床​​因素。方法：我们在五个葡萄牙医疗保健行政区和两个自治区的初级保健中心进行了横断面分析研究。我们使用了由卫生部（SPMS）信息部门提供的757位老年患者和来自自治区的家庭医生的随机样本。数据收集于2018年3月进行，我们研究了社会人口统计学特征，临床概况和药物治疗。我们使用了2015年《啤酒准则》来评估可能不适当的药物。进行了逻辑回归分析，以确定可能不合适的药物处方与其他变量之间的关联。结果：68.6％的样本中存在潜在的不当用药，而46.1％的样本中有两种以上。女性（OR = 1.56 [1.05至2.31]），慢性健康问题的数量（OR = 1.06 [1.01至1.13]），药理学亚类的数量（OR = 1.40 [1.30至1.51]）和处方人数（OR = 1.34 [1.09至1.65]）。最常见的是质子泵抑制剂，非甾体抗炎药和苯二氮卓类药物。结论：在葡萄牙，老年人中潜在的不适当用药是一种普遍现象。重要的是，医生应意识到这一问题，即在纵向护理的基础上。

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