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首页> 外文期刊>Patient Preference and Adherence >Predictors of medication nonadherence in patients with systemic lupus erythematosus in Sichuan: a cross-sectional study
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Predictors of medication nonadherence in patients with systemic lupus erythematosus in Sichuan: a cross-sectional study

机译：四川系统性红斑狼疮患者药物不依从性的预测因素：横断面研究

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Purpose: The aim of this study was to determine the prevalence and predictors of medication nonadherence among patients with systemic lupus erythematosus (SLE) in Sichuan. Patients and methods: A cross-sectional investigation was performed. Participants were recruited by consecutive sampling from the Rheumatic Clinic of a university hospital between June and September 2016. Patients’ self-reported medication adherence was assessed by the eight-item Morisky Medication Adherence Scale. Additional surveys included patients’ demographics, and clinical and treatment characteristics. Logistic regression analysis was used to identify the predictors of medication nonadherence. Results: A total of 140 patients were included in analysis. The percentage of patients classified as nonadherent to medication was 75%. Low education, rural residency, childlessness, limited comprehension of medication instructions, side effects experienced, dissatisfaction with treatment and better physical health were associated with an increased risk of nonadherence. Conclusion: This study demonstrated a high prevalence of medication nonadherence among SLE patients in Sichuan, and factors associated with the nonadherence are multifaceted. Interventions for these factors, such as appropriate adjustment of the service resources for patients with rheumatic disease in rural communities and improved communication between the health care providers and the patients, may contribute to improve the medication adherence of this cohort.
机译：目的：本研究旨在确定四川省系统性红斑狼疮（SLE）患者中药物不依从的患病率和预测因素。患者和方法：进行横断面调查。通过在2016年6月至9月之间从大学医院的风湿病诊所连续采样来招募参与者。患者的自我报告的药物依从性通过八项Morisky药物依从性量表进行评估。其他调查包括患者的人口统计资料，临床和治疗特征。 Logistic回归分析用于确定药物不依从性的预测因素。结果：共纳入140例患者。分类为不坚持用药的患者百分比为75％。受教育程度低，在农村居住，无子女，对用药说明的理解有限，经历的副作用，对治疗的不满意以及身体健康的改善与不依从的风险增加相关。结论：该研究表明四川省SLE患者中药物不依从的患病率很高，并且与药物不依从有关的因素是多方面的。对这些因素的干预，例如适当调整农村社区风湿病患者的服务资源以及改善医疗服务提供者与患者之间的沟通，可能有助于改善该人群的药物依从性。

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