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首页> 外文期刊>Patient Preference and Adherence >Excessive daytime sleepiness and adherence to antihypertensive medications among Blacks: analysis of the counseling African Americans to control hypertension (CAATCH) trial
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Excessive daytime sleepiness and adherence to antihypertensive medications among Blacks: analysis of the counseling African Americans to control hypertension (CAATCH) trial

机译:黑人白天过度嗜睡和坚持服用降压药:非洲裔美国人控制高血压咨询(CAATCH)试验的分析

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Background: Excessive daytime sleepiness (EDS) often occurs as a result of insufficient sleep, sleep apnea, illicit substance use, and other medical and psychiatric conditions. This study tested the hypothesis that blacks exhibiting EDS would have poorer self-reported adherence to hypertensive medication using cross-sectional data from the Counseling African-Americans to Control Hypertension (CAATCH) trial. Methods: A total of 1,058 hypertensive blacks (average age 57±12 years) participated in CAATCH, a randomized controlled trial evaluating the effectiveness of a multilevel intervention for participants who receive care from community health centers in New York City. Data analyzed in this study included baseline sociodemographics, medical history, EDS, and medication adherence. We used the Epworth Sleepiness Scale, with a cutoff score of ≥10, to define EDS. Medication adherence was measured using an abbreviated Morisky Medication Adherence scale, with a score >0 indicating nonadherence. Results: Of the sample, 71% were female, 72% received at least a high school education, 51% reported a history of smoking, and 33% had a history of alcohol consumption. Overall, 27% of the participants exhibited EDS, and 44% of those who exhibited EDS were classified as adherent to prescribed antihypertensive medications. Multivariable logistic regression analysis, adjusting for effects of age, body mass index, sex, education, and smoking and drinking history indicated that participants who exhibited EDS were more than twice as likely to be nonadherent (odds ratio 2.28, 95% confidence interval 1.42–3.67, P<0.001). Conclusion: Analysis of the CAATCH data showed a high prevalence of EDS among hypertensive blacks. EDS is a significant predictor of nonadherence to prescribed medications for hypertension. These findings point to a modifiable variable that can be targeted in future interventions focusing on medication adherence.
机译:背景:白天过度嗜睡(EDS)通常是由于睡眠不足,睡眠呼吸暂停,使用违禁药物以及其他医学和精神疾病引起的。这项研究使用咨询非裔美国人控制高血压(CAATCH)试验的横断面数据,验证了具有EDS的黑人自我报告的依从性较差的假设。方法:共有1,058名高血压黑人(平均年龄57±12岁)参加了CAATCH,这是一项随机对照试验,评估了多级干预对从纽约市社区卫生中心接受治疗的参与者的有效性。在这项研究中分析的数据包括基线社会人口统计学,病史,EDS和药物依从性。我们使用截止得分≥10的爱泼华嗜睡量表来定义EDS。使用缩写的Morisky药物依从性量表测量药物依从性,得分> 0表示不依从。结果:在样本中,女性占71%,至少具有高中文化程度的占72%,有吸烟史的占51%,有饮酒史的占33%。总体而言,有27%的受试者表现出EDS,而有44%的表现出EDS的受试者被归类为遵从处方降压药。多变量logistic回归分析(针对年龄,体重指数,性别,教育程度以及吸烟和饮酒史的影响进行了调整)表明,表现出EDS的参与者不依从的可能性是其两倍以上(优势比2.28,95%置信区间1.42– 3.67,P <0.001)。结论:对CAATCH数据的分析表明,高血压黑人中EDS的患病率很高。 EDS是不遵守高血压处方药的重要预测指标。这些发现指向一个可修改的变量,该变量可以在将来针对药物依从性的干预措施中作为目标。

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