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首页> 外文期刊>Patient Preference and Adherence >Intranasal fentanyl for pain control: current status with a focus on patient considerations
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Intranasal fentanyl for pain control: current status with a focus on patient considerations

机译：鼻内芬太尼用于疼痛控制：当前状态，着重于患者考虑因素

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Abstract: Of several newer delivery systems under development and investigation for the administration of opioids, the intranasal route has received a substantial amount of attention. Intranasal administration is a convenient form of delivery that is applicable to several opioids. It has the potential for self-administration, combined with a rapid onset of action, allowing for patient-controlled analgesia. In clinical practice, intranasal administration has been found to be a reliable drug delivery method that is familiar to patients. Intranasal opioids have proven to be useful in both in-hospital and out-of-hospital pain management settings. Fentanyl, a highly lipophilic step 3 opioid, has been evaluated for intranasal administration. The purpose of this review is to examine the role of the nasal route of opioid administration and examine the evidence base for the use of fentanyl intranasally.
机译：摘要：在正在开发和研究中的用于阿片类药物给药的几种较新的递送系统中，鼻内途径已引起广泛关注。鼻内给药是一种适用于几种阿片类药物的方便递送形式。它具有自我给药的潜力，并且起效迅速，可以进行患者自控镇痛。在临床实践中，已经发现鼻内给药是患者熟悉的可靠的药物递送方法。鼻内阿片类药物已被证明可在医院内和院外的疼痛管理环境中使用。芬太尼是一种高度亲脂性的第3步阿片类药物，已被评估用于鼻内给药。这篇综述的目的是检查阿片类药物鼻腔给药途径的作用，并检查鼻内使用芬太尼的证据基础。

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