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The impact of HIV clinical pharmacists on HIV treatment outcomes: a systematic review

机译:HIV临床药剂师对HIV治疗结果的影响:系统评价

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Objective: Due to the rapid proliferation of human immunodeficiency virus (HIV) treatment options, there is a need for health care providers with knowledge of antiretroviral therapy intricacies. In a HIV multidisciplinary care team, the HIV pharmacist is well-equipped to provide this expertise. We conducted a systematic review to assess the impact of HIV pharmacists on HIV clinical outcomes.Methods: We searched six electronic databases from January 1, 1980 to June 1, 2011 and included all quantitative studies that examined pharmacist's roles in the clinical care of HIV-positive adults. Primary outcomes were antiretroviral adherence, viral load, and CD4+ cell count and secondary outcomes included health care utilization parameters, antiretroviral modifications, and other descriptive variables.Results: Thirty-two publications were included. Despite methodological limitation, the involvement of HIV pharmacists was associated with statistically significant adherence improvements and positive impact on viral suppression in the majority of studies.Conclusion: This systematic review provides evidence of the beneficial impact of HIV pharmacists on HIV treatment outcomes and offers suggestions for future research.
机译:目的:由于人类免疫缺陷病毒(HIV)的治疗选择迅速扩散,因此需要具有抗逆转录病毒疗法复杂性知识的卫生保健提供者。在HIV多学科护理团队中,HIV药剂师具备了提供这种专业知识的设备齐全。我们进行了系统的评估,以评估HIV药剂师对HIV临床结果的影响。方法:我们检索了1980年1月1日至2011年6月1日的六个电子数据库,并纳入了所有定量研究,研究了药剂师在HIV临床护理中的作用-积极的成年人。主要结局为抗逆转录病毒依从性,病毒载量和CD4 +细胞计数,次要结局包括卫生保健利用率参数,抗逆转录病毒修饰和其他描述性变量。结果:包括32篇出版物。尽管方法学上存在局限性,但在大多数研究中,HIV药剂师的参与仍具有统计学上的显着依从性改善和对病毒抑制的积极影响。结论:这项系统的综述提供了证据,证明了HIV药剂师对HIV治疗结果的有益影响并提供了建议未来的研究。

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