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首页> 外文期刊>Patient Preference and Adherence >Preferences for oral versus intravenous adjuvant chemotherapy among early breast cancer patients
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Preferences for oral versus intravenous adjuvant chemotherapy among early breast cancer patients

机译：早期乳腺癌患者口服和静脉辅助化疗的偏爱

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Purpose: The purpose of this study was to evaluate preferences for oral versus intravenous adjuvant chemotherapy among early breast cancer patients (UMIN-CTR number UMIN000004696). Patients and methods: Eighty-two postmenopausal women with estrogen receptor-positive, human epidermal growth-factor receptor 2-negative breast cancer who had completed adjuvant chemotherapy were asked about their preferred route of administration of chemotherapy and the reason. Women also answered questions about their physical and psychological status and quality of life during chemotherapy. Results: Patients who had received oral chemotherapy preferred it more frequently than those who had received intravenous chemotherapy (100% versus 37%, respectively, chi-square =15.5; P<0.001). Patients who preferred the same route of administration of chemotherapy as they had previously received showed a significantly better psychological status during chemotherapy compared with those who preferred a different route. Conclusion: Our study showed that preferences for oral and intravenous chemotherapy strongly depended on the actual prior administration of chemotherapy and patients' own experiences during chemotherapy.
机译：目的：本研究的目的是评估早期乳腺癌患者（UMIN-CTR编号UMIN000004696）对口服辅助化疗还是静脉辅助化疗的偏好。患者和方法：询问了完成辅助化疗的八十二名绝经后雌激素受体阳性，人表皮生长因子受体2-阴性乳腺癌的妇女，其化疗的首选给药途径及其原因。妇女还回答了有关她们在化疗期间的身体和心理状况以及生活质量的问题。结果：接受口服化疗的患者比接受静脉化疗的患者更偏爱口服化疗（分别为100％和37％，卡方= 15.5; P <0.001）。与那些以前选择了相同途径的患者相比，那些以前选择了相同的化疗途径的患者在化疗期间表现出明显更好的心理状态。结论：我们的研究表明，口服和静脉化疗的偏好在很大程度上取决于实际的既往化疗方案和患者在化疗期间的经验。

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