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首页> 外文期刊>Patient Preference and Adherence >Antibiotic use for pneumonia among children under-five at a pediatric hospital in Dhaka city, Bangladesh
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Antibiotic use for pneumonia among children under-five at a pediatric hospital in Dhaka city, Bangladesh

机译：孟加拉国达卡市一家儿科医院五岁以下儿童的抗生素治疗肺炎

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Background: Pneumonia has been the leading cause of morbidity and mortality among children under 5 for more than 3 decades, particularly in low-income countries like Bangladesh. The World Health Organization (WHO) developed a pneumonia case management strategy which included the use of antibiotics for both primary and hospital-based care. This study aims to describe antibiotic usage for treating pneumonia in children in a private pediatric teaching hospital in Dhaka, Bangladesh. Methods: We conducted this cross-sectional study among children <5 years old who were admitted to a private pediatric hospital in Dhaka with a diagnosis of pneumonia in November 2012. Results: We enrolled 80 children during the study period. Among them, 28 (35.4%) were underweight, 14 (17.7%) were moderately underweight, and 13 (16.5%) were severely underweight. On the basis of WHO classification (2005), 43 children (54%) had severe pneumonia and 37 (46%) had very severe pneumonia, as diagnosed by the research physician. Among the prescribed antibiotics in the hospital, parenteral ceftriaxone was the most common 40 (50%), followed by cefotaxime plus amikacin 14 (17.5%), cefuroxime 7 (8.8%), ceftazidime plus amikacin 6 (7.5%), ceftriaxone plus amikacin 3 (3.8%), meropenem 2 (2.5%), cefepime 2 (2.5%), and cefotaxime 2 (2.5%). Conclusion: Despite the WHO pneumonia treatment strategy, the inappropriate use of higher-generation cephalosporin and carbapenem was high in the study hospital. The results underscore the noncompliance with the WHO guidelines of antibiotic use and the importance of enforcing regulatory policy of the rational use of antibiotics for treating hospitalized children with pneumonia. Following these guidelines may help prevent increased antimicrobial resistance.
机译：背景：在过去的3个多世纪中，肺炎一直是5岁以下儿童发病和死亡的主要原因，尤其是在孟加拉等低收入国家。世界卫生组织（世卫组织）制定了一项肺炎病例管理战略，其中包括在基层和医院护理中使用抗生素。这项研究旨在描述在孟加拉国达卡的一家私人儿科教学医院中使用抗生素治疗儿童肺炎的方法。方法：2012年11月，我们在达卡的一家私人儿科医院接受诊断为肺炎的5岁以下儿童中进行了这项横断面研究。结果：在研究期间，我们招募了80名儿童。其中，体重不足的28人（35.4％），中度体重不足的14人（17.7％），重度体重不足的13人（16.5％）。根据研究医师的诊断，根据WHO的分类（2005年），有43名儿童（54％）患有严重的肺炎，而37名儿童（46％）患有严重的肺炎。在医院开出的处方抗生素中，肠胃外头孢曲松是最常见的40种（50％），其次是头孢噻肟+阿米卡星14（17.5％），头孢呋辛7（8.8％），头孢他啶+阿米卡星6（7.5％），头孢曲松+阿米卡星3（3.8％），美洛培南2（2.5％），头孢吡肟2（2.5％）和头孢噻肟2（2.5％）。结论：尽管采用了WHO肺炎治疗策略，但研究医院仍普遍不适当使用上一代头孢菌素和碳青霉烯。结果强调了不符合WHO的抗生素使用指南，以及执行合理使用抗生素治疗住院肺炎儿童的监管政策的重要性。遵循这些准则可能有助于防止增加的抗菌素耐药性。

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