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首页> 外文期刊>Patient Preference and Adherence >Humanistic outcomes and patient acceptance of the pharmacist-led medication review “Polymedication Check” in primary care in Switzerland: a prospective randomized controlled trial
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Humanistic outcomes and patient acceptance of the pharmacist-led medication review “Polymedication Check” in primary care in Switzerland: a prospective randomized controlled trial

机译：瑞士初级保健中以人为本的结果和药剂师指导下的药物审查“综合药物检查”对患者的接受：一项前瞻性随机对照试验

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Background: Since 2010, Swiss pharmacists have been offering their patients a Polymedication Check (PMC), a new cognitive pharmacy service in the form of a medication review for patients taking ≥4 prescribed medicines for a period >3 months. While a first publication of this project reported on the impact of the PMC on patients’ adherence, the present paper focuses on humanistic outcomes. Methods: This randomized controlled trial was conducted in 54 Swiss community pharmacies. After recruitment, the intervention group underwent a PMC in the pharmacy (T-0) and 28 weeks after T-0 (T-28), while the control group did not receive the PMC until 28 weeks after the study started (T-28). A clinical psychologist, blinded to the intervention, interviewed the patients 2 weeks (T-2) and 16 weeks (T-16) after T-0. Interviewer and patient both rated patient’s knowledge of own medicines use. Furthermore, patients reported satisfaction with their pharmacy and appraisal of their medicines use. The availability of a written medication plan was assessed at T-16. Acceptance of the service was measured using a patient’s self-report questionnaire at T-28. Results: General linear model analysis for knowledge about medicines revealed a significant effect on the factor “group” ( F =5.86, p =0.016), indicating that the intervention group had higher ratings for knowledge about their medication at T-2 and T-16 compared to controls. The majority (83%) of patients judged the counseling by the pharmacist as being helpful for their daily medication management. Availability of a written medication plan was comparable in both groups (52.5% vs 52.7%, p >0.05). Conclusion: For the first time, the benefits of a complex pharmacist-led intervention were evaluated in Swiss primary care with a randomized controlled trial. The PMC increased patients’ subjective knowledge of their medicines compared to no medication review. The effect remained sustainable over time. Recommendations resulting from the pharmacist-led service were highly appreciated by the patients.
机译：背景：自2010年以来，瑞士药剂师一直在为患者提供多药检查（PMC），这是一种新的认知药房服务，以药物复查的形式，针对服用≥4种处方药且持续时间超过3个月的患者。虽然该项目的第一篇出版物报道了PMC对患者依从性的影响，但本文重点关注人文结果。方法：该随机对照试验在54家瑞士社区药店进行。招募后，干预组在药房（T-0）和T-0后28周（T-28）进行了一次PMC，而对照组直到研究开始后28周才接受PMC。 ）。一位不愿干预的临床心理学家在T-0后2周（T-2）和16周（T-16）采访了患者。访调员和患者都对患者对自己使用药物的知识进行了评估。此外，患者报告对他们的药房和对其药物使用的评估感到满意。在T-16评估了书面药物治疗计划的可用性。在T-28时使用患者的自我报告调查表评估了对服务的接受程度。结果：对药物知识的一般线性模型分析显示，对因素“组”有显着影响（F = 5.86，p = 0.016），表明干预组对他们在T-2和T-与对照组相比为16。大多数患者（83％）认为药剂师的辅导对他们的日常用药管理很有帮助。两组患者书面用药计划的可用性均相当（52.5％比52.7％，p> 0.05）。结论：这是首次在瑞士的初级保健中通过一项随机对照试验评估了由药剂师主导的复杂干预措施的益处。与不进行药物审查相比，PMC增加了患者对药物的主观知识。随着时间的推移，这种影响仍然可持续。患者高度赞赏由药剂师主导的服务提出的建议。

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