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Bromfenac ophthalmic solution for the treatment of postoperative ocular pain and inflammation: safety, efficacy, and patient adherence

机译：溴芬酸眼药水用于治疗术后眼部疼痛和炎症：安全性，疗效和患者依从性

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Abstract: Ophthalmic nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used by clinicians to manage ocular inflammation and pain following cataract surgery. Over the past decade, the US Food and Drug Administration has approved multiple topical NSAIDs for these purposes, including several reformulated products. One of these medications, bromfenac ophthalmic solution, has a long and extensive history, with proven efficacy and safety in patients following cataract surgery. The evolution of bromfenac ophthalmic solution over the years has involved either lowering the concentration of the active ingredient or extending the dosing interval to improve patient adherence/compliance. This review will focus on the history and progression of bromfenac ophthalmic solution and report the available patient preference and adherence data regarding this ocular NSAID throughout its evolution.
机译：摘要：眼科非甾体类抗炎药（NSAID）是临床医生通常用于治疗白内障手术后的眼部炎症和疼痛的药物。在过去的十年中，美国食品药品监督管理局已经批准了多种用于这些目的的NSAID局部用药，包括几种重新配制的产品。这些药物之一是溴芬酸眼用溶液剂，具有悠久而广泛的历史，在白内障手术后的患者中已证明具有疗效和安全性。多年来，溴芬酸滴眼液的发展涉及降低活性成分的浓度或延长给药间隔以改善患者依从性/依从性。这篇综述将侧重于溴芬酸眼药水的历史和进展，并报告有关该眼用非甾体抗炎药在整个进化过程中可获得的患者偏爱和依从性数据。

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