...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Patient Preference and Adherence >Two-year clinical outcomes after coronary drug-eluting stent placement in Chinese men and women: a multicenter, prospective registry study
【24h】

Two-year clinical outcomes after coronary drug-eluting stent placement in Chinese men and women: a multicenter, prospective registry study

机译：中国男性和女性冠状动脉药物洗脱支架置入术后两年的临床结果：一项多中心，前瞻性研究

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Previous studies have reported a discrepancy in baseline characteristics and outcomes after percutaneous coronary intervention between men and women. However, this finding has never been verified in the Chinese population. The present study analyzed two-year clinical outcomes after placement of coronary drug-eluting stents in Chinese men and women. Methods: From January 2005 to December 2010, a total of 3804 Chinese patients (2776 men, 1028 women) who underwent drug-eluting stent implantation were studied prospectively. The primary endpoint was the composite major adverse cardiac event (MACE) rate, including myocardial infarction, cardiac death, and target vessel revascularization at two years. Stent thrombosis served as the safety endpoint. Propensity score matching was used to compare the adjusted MACE rate between the two groups. Results: At two-year follow-up, unadjusted rates of myocardial infarction, non-ST segment elevation myocardial infarction, target vessel revascularization, and MACE were significantly different between men (6.84%, 4.6%, 13.1%, and 21.7%, respectively) and women (3.8% [P = 0.001], 2.0% [P < 0.001] 10.3% [P = 0.025], and 16.3% [P < 0.001], respectively). After propensity score matching, there were no significant differences in composite MACE and individual endpoints at two years between the genders. Conclusion: Despite all the unfavorable risk factor clustering in women and complex coronary disease in men, the two-year clinical outcomes after coronary stent placement were comparable between Chinese women and men.
机译：背景：先前的研究报道了男女之间经皮冠状动脉介入治疗后的基线特征和结果存在差异。但是，这一发现从未在中国人口中得到证实。本研究分析了中国男性和女性放置冠状药物洗脱支架后的两年临床结果。方法：自2005年1月至2010年12月，共对3804名中国患者进行了药物洗脱支架植入术的研究，其中男性2776例，女性1028例。主要终点是两年中的复合性主要不良心脏事件（MACE）率，包括心肌梗塞，心脏死亡和目标血管血运重建。支架血栓形成是安全终点。倾向得分匹配用于比较两组之间调整后的MACE率。结果：在两年的随访中，男性的心肌梗死，非ST段抬高型心肌梗死，靶血管血运重建和MACE的未调整率差异显着（分别为6.84％，4.6％，13.1％和21.7％） ）和女性（分别为3.8％[P = 0.001]，2.0％[P <0.001]，10.3％[P = 0.025]和16.3％[P <0.001]）。倾向得分匹配后，性别之间的复合MACE和个体终点在两年之间没有显着差异。结论：尽管女性中存在所有不利的危险因素聚类，男性中复杂的冠心病，但在中国女性和男性中，冠状动脉支架置入术后的两年临床结局相当。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号