...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Sensing and Bio-Sensing Research >DNA-directed self-assembly of three-dimensional plasmonic nanostructures for detection by surface-enhanced Raman scattering (SERS)
【24h】

DNA-directed self-assembly of three-dimensional plasmonic nanostructures for detection by surface-enhanced Raman scattering (SERS)

机译：用于表面增强拉曼散射（SERS）检测的三维等离子纳米结构的DNA定向自组装

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Abstract Surface-enhanced Raman scattering (SERS) is a promising technology owing to its single-molecular sensitivity and molecular specificity. However, producing strong and stable {SERS} signal from plasmonic nanostructures remains a challenge. Herein, we present a facile generation of SERS-active nanomaterials by organizing metallic nanoparticles onto dye-labeled three-dimensional {DNA} nanostructures. Stable formations of metal clusters with the dye located in hot spots enabled detection of {SERS} signals. {SERS} signals were further regulated via interaction of pyramidal {DNA} scaffold with target biomolecules. We believe our SERS-active nanomaterials with controllable geometry and reversible {SERS} effects meet significant requirements for practical SERS-based sensors. By integrating versatile properties of {DNA} and introducing various Raman dyes into plasmonic nanostructures, the emergence of powerful and multiplexed biosensors should be possible.
机译：摘要表面增强拉曼散射（SERS）由于其单分子敏感性和分子特异性而成为一项很有前途的技术。然而，从等离子体纳米结构产生强而稳定的{SERS}信号仍然是一个挑战。本文中，我们通过将金属纳米颗粒组织到染料标记的三维{DNA}纳米结构上，提出了一种简便的SERS活性纳米材料。染料位于热点的金属簇的稳定形成使得能够检测{SERS}信号。 {SERS}信号通过锥体{DNA}支架与靶标生物分子的相互作用进一步调控。我们相信，具有可控几何形状和可逆{SERS}效应的SERS活性纳米材料可以满足基于实用SERS的传感器的重要要求。通过整合{DNA}的通用特性并将各种拉曼染料引入等离激元纳米结构，功能强大且多重化的生物传感器应会出现。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号